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Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 162, 期号: 2, 页码: 570-581
作者:  Hornung, Michael W.;  Korte, Joseph J.;  Olker, Jennifer H.;  Denny, Jeffrey S.;  Knutsen, Carsten;  Hartig, Phillip C.;  Cardon, Mary C.;  Degitz, Sigmund J.
收藏  |  浏览/下载:17/0  |  提交时间:2019/05/04
Zebrafish Locomotor Responses Reveal Irritant Effects of Fine Particulate Matter Extracts and a Role for TRPA1 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 161, 期号: 2, 页码: 290-299
作者:  Stevens, Joey S.;  Padilla, Stephanie;  DeMarini, David M.;  Hunter, Deborah L.;  Martin, W. Kyle;  Thompson, Leslie C.;  Gilmour, M. Ian;  Hazari, Mehdi S.;  Farraj, Aimen K.
收藏  |  浏览/下载:31/0  |  提交时间:2019/05/04
Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 160, 期号: 1, 页码: 57-73
作者:  Hassan, Iman;  El-Masri, Hisham;  Kosian, Patricia A.;  Ford, Jermaine;  Degitz, Sigmund J.;  Gilbert, Mary E.
收藏  |  浏览/下载:28/0  |  提交时间:2019/05/04
Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 156, 期号: 2, 页码: 344-361
作者:  Martinovic-Weigelt, Dalma;  Mehinto, Alvine C.;  Ankley, Gerald T.;  Berninger, Jason P.;  Collette, Timothy W.;  Davis, John M.;  Denslow, Nancy D.;  Durhan, Elizabeth J.;  Eid, Evan;  Ekman, Drew R.;  Jensen, Kathleen M.;  Kahl, Michael D.;  LaLone, Carlie A.;  Teng, Quincy;  Villeneuve, Daniel L.
收藏  |  浏览/下载:36/0  |  提交时间:2019/05/04
Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 155, 期号: 1, 页码: 270-282
作者:  Marchitti, Satori A.;  Mazur, Christopher S.;  Dillingham, Caleb M.;  Rawat, Swati;  Sharma, Anshika;  Zastre, Jason;  Kenneke, John F.
收藏  |  浏览/下载:21/0  |  提交时间:2019/05/04
Editor's Highlight: Computational Modeling of Plasma Vitellogenin Alterations in Response to Aromatase Inhibition in Fathead Minnows 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 154, 期号: 1, 页码: 78-89
作者:  Cheng, Wan-Yun;  Zhang, Qiang;  Schroeder, Anthony;  Villeneuve, Daniel L.;  Ankley, Gerald T.;  Conolly, Rory
收藏  |  浏览/下载:11/0  |  提交时间:2019/05/04
Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 151, 期号: 1, 页码: 160-180
作者:  Friedman, Katie Paul;  Watt, Eric D.;  Hornung, Michael W.;  Hedge, Joan M.;  Judson, Richard S.;  Crofton, Kevin M.;  Houck, Keith A.;  Simmons, Steven O.
收藏  |  浏览/下载:23/0  |  提交时间:2019/05/04
Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 151, 期号: 1, 页码: 57-70
作者:  Leonard, Jeremy A.;  Tan, Yu-Mei;  Gilbert, Mary;  Isaacs, Kristin;  El-Masri, Hisham
收藏  |  浏览/下载:12/0  |  提交时间:2019/05/04
High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 150, 期号: 2, 页码: 323-332
作者:  Karmaus, Agnes L.;  Toole, Colleen M.;  Filer, Dayne L.;  Lewis, Kenneth C.;  Martin, Matthew T.
收藏  |  浏览/下载:31/0  |  提交时间:2019/05/04
Development of 3D-QSAR Model for Acetylcholinesterase Inhibitors Using a Combination of Fingerprint, Molecular Docking, and Structure-Based Pharmacophore Approaches 期刊论文
TOXICOLOGICAL SCIENCES, 2015, 卷号: 148, 期号: 1, 页码: 60-70
作者:  Lee, Sehan;  Barron, Mace G.
收藏  |  浏览/下载:17/0  |  提交时间:2019/05/04