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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 7
作者:  Xia, Menghang;  Huang, Ruili;  Shi, Qiang;  Boyd, Windy A.;  Zhao, Jinghua;  Sun, Nuo;  Rice, Julie R.;  Dunlap, Paul E.;  Hackstadt, Amber J.;  Bridge, Matt F.;  Smith, Marjolein V.;  Dai, Sheng;  Zheng, Wei;  Chu, Pei-Hsuan;  Gerhold, David;  Witt, Kristine L.;  DeVito, Michael;  Freedman, Jonathan H.;  Austin, Christopher P.;  Houck, Keith A.;  Thomas, Russell S.;  Paules, Richard S.;  Tice, Raymond R.;  Simeonov, Anton
收藏  |  浏览/下载:54/0  |  提交时间:2019/05/04
Accelerating the Pace of Chemical Risk Assessment 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2018, 卷号: 31, 期号: 5, 页码: 287-290
作者:  Kavlock, Robert J.;  Bahadori, Tina;  Barton-Maclaren, Tara S.;  Gwinn, Maureen R.;  Rasenberg, Mike;  Thomas, Russell S.
收藏  |  浏览/下载:25/0  |  提交时间:2019/05/04
Application of Gene Set Enrichment Analysis for Identification of Chemically Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk Assessment 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 157, 期号: 1, 页码: 85-99
作者:  Dean, Jeffry L.;  Zhao, Q. Jay;  Lambert, Jason C.;  Hawkins, Belinda S.;  Thomas, Russell S.;  Wesselkamper, Scott C.
收藏  |  浏览/下载:33/0  |  提交时间:2019/05/04
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 152, 期号: 2, 页码: 323-339
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Richard, Ann M.;  Knudsen, Thomas B.;  Shah, Imran;  Little, Stephen;  Wambaugh, John;  Setzer, R. Woodrow;  Kothya, Parth;  Phuong, Jimmy;  Filer, Dayne;  Smith, Doris;  Reif, David;  Rotroff, Daniel;  Kleinstreuer, Nicole;  Sipes, Nisha;  Xia, Menghang;  Huang, Ruili;  Crofton, Kevin;  Thomas, Russell S.
收藏  |  浏览/下载:33/0  |  提交时间:2019/05/04
Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2016, 卷号: 79, 页码: 12-24
作者:  Shah, Imran;  Liu, Jie;  Judson, Richard S.;  Thomas, Russell S.;  Patlewicz, Grace
收藏  |  浏览/下载:2/0  |  提交时间:2019/05/04
Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing 期刊论文
TOXICOLOGICAL SCIENCES, 2015, 卷号: 148, 期号: 1, 页码: 121-136
作者:  Wetmore, Barbara A.;  Wambaugh, John F.;  Allen, Brittany;  Ferguson, Stephen S.;  Sochaski, Mark A.;  Setzer, R. Woodrow;  Houck, Keith A.;  Strope, Cory L.;  Cantwell, Katherine;  Judson, Richard S.;  LeCluyse, Edward;  Clewell, Harvey J.;  Thomas, Russell S.;  Andersen, Melvin E.
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
The SEURAT-1 Approach towards Animal Free Human Safety Assessment 期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2015, 卷号: 32, 期号: 1, 页码: 9-24
作者:  Gocht, Tilman;  Berggren, Elisabet;  Ahr, Hans Juergen;  Cotgreave, Ian;  Cronin, Mark T. D.;  Daston, George;  Hardy, Barry;  Heinzle, Elmar;  Hescheler, Juergen;  Knight, Derek J.;  Mahony, Catherine;  Peschanski, Marc;  Schwarz, Michael;  Thomas, Russell S.;  Verfaillie, Catherine;  White, Andrew;  Whelan, Maurice
收藏  |  浏览/下载:32/0  |  提交时间:2019/05/04
SEURAT: Safety Evaluation Ultimately Replacing Animal Testing-Recommendations for future research in the field of predictive toxicology 期刊论文
ARCHIVES OF TOXICOLOGY, 2015, 卷号: 89, 期号: 1, 页码: 15-23
作者:  Daston, George;  Knight, Derek J.;  Schwarz, Michael;  Gocht, Tilman;  Thomas, Russell S.;  Mahony, Catherine;  Whelan, Maurice
收藏  |  浏览/下载:16/0  |  提交时间:2019/05/04
Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing 期刊论文
TOXICOLOGICAL SCIENCES, 2014, 卷号: 142, 期号: 1, 页码: 210-224
作者:  Wetmore, Barbara A.;  Allen, Brittany;  Clewell, Harvey J., III;  Parker, Timothy;  Wambaugh, John F.;  Almond, Lisa M.;  Sochaski, Mark A.;  Thomas, Russell S.
收藏  |  浏览/下载:22/0  |  提交时间:2019/05/04
In Vitro and Modelling Approaches to Risk Assessment from the US Environmental Protection Agency ToxCast Programme 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 卷号: 115, 期号: 1, 页码: 69-76
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Knudsen, Thomas;  Thomas, Russell S.;  Sipes, Nisha;  Shah, Imran;  Wambaugh, John;  Crofton, Kevin
收藏  |  浏览/下载:18/0  |  提交时间:2019/05/04