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Intravital imaging of mouse embryos 期刊论文
, 2020, 卷号: 368, 期号: 6487
作者:  Huang Q.;  Cohen M.A.;  Alsina F.C.;  Devlin G.;  Garrett A.;  McKey J.;  Havlik P.;  Rakhilin N.;  Wang E.;  Xiang K.;  Mathews P.;  Wang L.;  Bock C.;  Ruthig V.;  Wang Y.;  Negrete M.;  Wong C.W.;  Murthy P.K.L.;  Zhang S.;  Daniel A.R.;  Kirsch D.G.;  Kang Y.;  Capel B.;  Asokan A.;  Silver D.L.;  Jaenisch R.;  Shen X.
收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28
cell  embryo  embryonic development  imaging method  physiology  animal cell  animal experiment  article  autophagy (cellular)  brain cell  cell division  chimera  controlled study  diffusion  electroporation  embryo  female  microscopy  mouse  mouse embryo  neural crest cell  neurotransmission  nonhuman  placenta  retina  uterus  vascularization  viral gene delivery system  
Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia 期刊论文
, 2020, 卷号: 367, 期号: 6477
作者:  Uckelmann H.J.;  Kim S.M.;  Wong E.M.;  Hatton C.;  Giovinazzo H.;  Gadrey J.Y.;  Krivtsov A.V.;  Rücker F.G.;  Döhner K.;  McGeehan G.M.;  Levine R.L.;  Bullinger L.;  Vassiliou G.S.;  Armstrong S.A.
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28
antileukemic agent  methionine  unclassified drug  vtp 50469  biological development  cancer  cell  disease treatment  mutation  numerical model  oral health  acute myeloid leukemia  animal cell  animal experiment  animal model  antineoplastic activity  Article  cell proliferation  cell self-renewal  chromatin  controlled study  drug targeting  gene  gene mutation  leukemia cell  molecularly targeted therapy  mouse  mouse model  nonhuman  NPM1 gene  preleukemia  priority journal  Mus  
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Zhao P.;  Sun X.;  Chaggan C.;  Liao Z.;  Wong K.I.;  He F.;  Singh S.;  Loomba R.;  Karin M.;  Witztum J.L.;  Saltiel A.R.
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/28
6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile  adenosine phosphate  caspase 3  caspase 6  caspase 7  cytochrome c  hydroxymethylglutaryl coenzyme A reductase kinase  matrix metalloproteinase  apoptosis  cytochrome  enzyme  enzyme activity  inhibition  protein  rodent  AMPK signaling  animal experiment  animal model  animal tissue  apoptosis  Article  C57BL 6 mouse  cell death  controlled study  drug mechanism  enzyme activation  enzyme activity  enzyme inhibition  enzyme phosphorylation  enzyme repression  gene knockout  human  human cell  human tissue  liver cell  liver fibrosis  liver injury  male  mouse  nonalcoholic steatohepatitis  nonhuman  priority journal  protein cleavage  protein secretion