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| Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity 期刊论文 Science, 2021, 卷号: 371, 期号: 6531 作者: Blum T.R.; Liu H.; Packer M.S.; Xiong X.; Lee P.-G.; Zhang S.; Richter M.; Minasov G.; Satchell K.J.F.; Dong M.; Liu D.R. 收藏  |  浏览/下载:18/0  |  提交时间:2022/01/14 |
| Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody 期刊论文 Science, 2021, 卷号: 371, 期号: 6531 作者: Garrett Rappazzo C.; Tse L.V.; Kaku C.I.; Wrapp D.; Sakharkar M.; Huang D.; Deveau L.M.; Yockachonis T.J.; Herbert A.S.; Battles M.B.; O’Brien C.M.; Brown M.E.; Geoghegan J.C.; Belk J.; Peng L.; Yang L.; Hou Y.; Scobey T.D.; Burton D.R.; Nemazee D.; Dye J.M.; Voss J.E.; Gunn B.M.; McLellan J.S.; Baric R.S.; Gralinski L.E.; Walker L.M. 收藏  |  浏览/下载:50/0  |  提交时间:2022/01/14 |
| How directed evolution reshapes the energy landscape in an enzyme to boost catalysis 期刊论文 Science, 2020, 卷号: 370, 期号: 6523 作者: Otten R.; Pádua R.A.P.; Bunze H.A.; Nguyen V.; Pitsawong W.; Patterson M.; Sui S.; Perry S.L.; Cohen A.E.; Hilvert D.; Kern D. 收藏  |  浏览/下载:36/0  |  提交时间:2022/01/14 |
| Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文 Science, 2020, 卷号: 368, 期号: 6496 作者: Zhang L.; Zhao Y.; Gao Y.; Wu L.; Gao R.; Zhang Q.; Wang Y.; Wu C.; Wu F.; Gurcha S.S.; Veerapen N.; Batt S.M.; Zhao W.; Qin L.; Yang X.; Wang M.; Zhu Y.; Zhang B.; Bi L.; Zhang X.; Yang H.; Guddat L.W.; Xu W.; Wang Q.; Li J.; Besra G.S.; Rao Z. 收藏  |  浏览/下载:16/0  |  提交时间:2022/01/14 |
| Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation 期刊论文 Science, 2020, 卷号: 370, 期号: 6523 作者: Townsend C.; Leelaram M.N.; Agafonov D.E.; Dybkov O.; Will C.L.; Bertram K.; Urlaub H.; Kastner B.; Stark H.; Lührmann R. 收藏  |  浏览/下载:17/0  |  提交时间:2022/01/14 |
| A bound reaction intermediate sheds light on the mechanism of nitrogenase 期刊论文 Science, 2018, 卷号: 359, 期号: 6383 作者: Sippel D.; Rohde M.; Netzer J.; Trncik C.; Gies J.; Grunau K.; Djurdjevic I.; Decamps L.; Andrade S.L.A.; Einsle O. 收藏  |  浏览/下载:11/0  |  提交时间:2022/01/14 |
| Ligand binding to the FeMo-cofactor: Structures of co-bound and reactivated nitrogenase 期刊论文 Science, 2014, 卷号: 345, 期号: 6204 作者: Spatzal T.; Perez K.A.; Einsle O.; Howard J.B.; Rees D.C. 收藏  |  浏览/下载:18/0  |  提交时间:2022/01/14 |
| Radical SAM-dependent carbon insertion into the nitrogenase M-cluster 期刊论文 Science, 2012, 卷号: 337, 期号: 6102 作者: Wiig J.A.; Hu Y.; Lee C.C.; Ribbe M.W. 收藏  |  浏览/下载:11/0  |  提交时间:2022/01/14 |