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Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity 期刊论文
Science, 2021, 卷号: 371, 期号: 6531
作者:  Blum T.R.;  Liu H.;  Packer M.S.;  Xiong X.;  Lee P.-G.;  Zhang S.;  Richter M.;  Minasov G.;  Satchell K.J.F.;  Dong M.;  Liu D.R.
收藏  |  浏览/下载:18/0  |  提交时间:2022/01/14
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody 期刊论文
Science, 2021, 卷号: 371, 期号: 6531
作者:  Garrett Rappazzo C.;  Tse L.V.;  Kaku C.I.;  Wrapp D.;  Sakharkar M.;  Huang D.;  Deveau L.M.;  Yockachonis T.J.;  Herbert A.S.;  Battles M.B.;  O’Brien C.M.;  Brown M.E.;  Geoghegan J.C.;  Belk J.;  Peng L.;  Yang L.;  Hou Y.;  Scobey T.D.;  Burton D.R.;  Nemazee D.;  Dye J.M.;  Voss J.E.;  Gunn B.M.;  McLellan J.S.;  Baric R.S.;  Gralinski L.E.;  Walker L.M.
收藏  |  浏览/下载:50/0  |  提交时间:2022/01/14
How directed evolution reshapes the energy landscape in an enzyme to boost catalysis 期刊论文
Science, 2020, 卷号: 370, 期号: 6523
作者:  Otten R.;  Pádua R.A.P.;  Bunze H.A.;  Nguyen V.;  Pitsawong W.;  Patterson M.;  Sui S.;  Perry S.L.;  Cohen A.E.;  Hilvert D.;  Kern D.
收藏  |  浏览/下载:36/0  |  提交时间:2022/01/14
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol 期刊论文
Science, 2020, 卷号: 368, 期号: 6496
作者:  Zhang L.;  Zhao Y.;  Gao Y.;  Wu L.;  Gao R.;  Zhang Q.;  Wang Y.;  Wu C.;  Wu F.;  Gurcha S.S.;  Veerapen N.;  Batt S.M.;  Zhao W.;  Qin L.;  Yang X.;  Wang M.;  Zhu Y.;  Zhang B.;  Bi L.;  Zhang X.;  Yang H.;  Guddat L.W.;  Xu W.;  Wang Q.;  Li J.;  Besra G.S.;  Rao Z.
收藏  |  浏览/下载:16/0  |  提交时间:2022/01/14
Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation 期刊论文
Science, 2020, 卷号: 370, 期号: 6523
作者:  Townsend C.;  Leelaram M.N.;  Agafonov D.E.;  Dybkov O.;  Will C.L.;  Bertram K.;  Urlaub H.;  Kastner B.;  Stark H.;  Lührmann R.
收藏  |  浏览/下载:17/0  |  提交时间:2022/01/14
A bound reaction intermediate sheds light on the mechanism of nitrogenase 期刊论文
Science, 2018, 卷号: 359, 期号: 6383
作者:  Sippel D.;  Rohde M.;  Netzer J.;  Trncik C.;  Gies J.;  Grunau K.;  Djurdjevic I.;  Decamps L.;  Andrade S.L.A.;  Einsle O.
收藏  |  浏览/下载:11/0  |  提交时间:2022/01/14
Ligand binding to the FeMo-cofactor: Structures of co-bound and reactivated nitrogenase 期刊论文
Science, 2014, 卷号: 345, 期号: 6204
作者:  Spatzal T.;  Perez K.A.;  Einsle O.;  Howard J.B.;  Rees D.C.
收藏  |  浏览/下载:18/0  |  提交时间:2022/01/14
Radical SAM-dependent carbon insertion into the nitrogenase M-cluster 期刊论文
Science, 2012, 卷号: 337, 期号: 6102
作者:  Wiig J.A.;  Hu Y.;  Lee C.C.;  Ribbe M.W.
收藏  |  浏览/下载:11/0  |  提交时间:2022/01/14