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Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Krawczyk K.;  Xue S.;  Buchmann P.;  Charpin-El-Hamri G.;  Saxena P.;  Hussherr M.-D.;  Shao J.;  Ye H.;  Xie M.;  Fussenegger M.
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/28
cell  diabetes  hormone  peptide  real time  rodent  Mus  calcium channel L type  inwardly rectifying potassium channel  inwardly rectifying potassium channel subunit Kir2.1  L-type calcium channel alpha(1C)  animal  calcium signaling  cell engineering  devices  electrostimulation  experimental diabetes mellitus  genetic transcription  genetics  HEK293 cell line  human  insulin dependent diabetes mellitus  insulin release  male  metabolism  mouse  pancreas islet beta cell  prostheses and orthoses  transgene  wireless communication  Animals  Bionics  Calcium Channels, L-Type  Calcium Signaling  Cell Engineering  Diabetes Mellitus, Experimental  Diabetes Mellitus, Type 1  Electric Stimulation  HEK293 Cells  Humans  Insulin Secretion  Insulin-Secreting Cells  Male  Mice  Potassium Channels, Inwardly Rectifying  Prostheses and Implants  Transcription, Genetic  Transgenes  Wireless Technology  
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells 期刊论文
, 2020, 卷号: 368, 期号: 6494
作者:  Zhou Z.;  He H.;  Wang K.;  Shi X.;  Wang Y.;  Su Y.;  Wang Y.;  Li D.;  Liu W.;  Zhang Y.;  Shen L.;  Han W.;  Shen L.;  Ding J.;  Shao F.
收藏  |  浏览/下载：26/0  |  提交时间：2020/07/28
cell  cell component  cytology  enzyme  enzyme activity  gene expression  immunity  tumor  Mus  gamma interferon  granzyme  GSDMB protein, human  GZMA protein, human  pore forming cytotoxic protein  tumor protein  animal  Bagg albino mouse  chemistry  cytotoxic T lymphocyte  enzymology  genetics  HEK293 cell line  human  immunology  metabolism  mouse  natural killer cell  neoplasm  pathology  protein degradation  protein domain  pyroptosis  transgenic mouse  Animals  Granzymes  HEK293 Cells  Humans  Interferon-gamma  Killer Cells, Natural  Mice  Mice, Inbred BALB C  Mice, Transgenic  Neoplasm Proteins  Neoplasms  Pore Forming Cytotoxic Proteins  Protein Domains  Proteolysis  Pyroptosis  T-Lymphocytes, Cytotoxic