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| CFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation 期刊论文 , 2020, 卷号: 367, 期号: 6484 作者: Muendlein H.I.; Jetton D.; Connolly W.M.; Eidell K.P.; Magri Z.; Smirnova I.; Poltorak A.
 收藏  |  浏览/下载:49/0  |  提交时间:2020/07/28 FLICE inhibitory protein interleukin 1beta lipopolysaccharide messenger RNA succinate dehydrogenase (ubiquinone) Casp1 protein, mouse caspase 8 Cflar protein, mouse cryopyrin FLICE inhibitory protein IL1B protein, mouse inflammasome interleukin 1beta interleukin 1beta converting enzyme lipopolysaccharide succinate dehydrogenase (ubiquinone) cell enzyme activity inhibition maturation protein animal cell animal experiment Article bone marrow derived macrophage cell death cell protection complex formation controlled study cytokine release in vitro study inflammation mouse nonhuman priority journal protein analysis protein degradation protein function protein interaction pyroptosis animal gene knockdown genetics immunology macrophage macrophage activation metabolism physiology Murinae Animals CASP8 and FADD-Like Apoptosis Regulating Protein Caspase 1 Caspase 8 Electron Transport Complex II Gene Knockdown Techniques Inflammasomes Interleukin-1beta Lipopolysaccharides Macrophage Activation Macrophages Mice NLR Family, Pyrin Domain-Containing 3 Protein Pyroptosis |
| Hydrophobic zeolite modification for in situ peroxide formation in methane oxidation to methanol 期刊论文 , 2020, 卷号: 367, 期号: 6474 作者: Jin Z.; Wang L.; Zuidema E.; Mondal K.; Zhang M.; Zhang J.; Wang C.; Meng X.; Yang H.; Mesters C.; Xiao F.-S.
 收藏  |  浏览/下载:252/0  |  提交时间:2020/07/28 aluminosilicate zeolite carbon dioxide carbon monoxide formaldehyde gold nanoparticle hydrogen peroxide methane methanol palladium nanoparticle silicon dioxide unclassified drug zeolite aluminosilicate catalyst diffusion hydrogen hydrogen peroxide methane methanol oxidation oxygen Article carbon nuclear magnetic resonance catalyst chemical reaction concentration (parameter) diffusion energy dispersive X ray spectroscopy Fourier transform infrared spectroscopy hydrophobicity isotherm nanoencapsulation nuclear magnetic resonance oxidation priority journal scanning electron microscopy silicon nuclear magnetic resonance stoichiometry synthesis transmission electron microscopy X ray crystallography |
| A general method to synthesize and sinter bulk ceramics in seconds 期刊论文 , 2020, 卷号: 368, 期号: 6490 作者: Wang C.; Ping W.; Bai Q.; Cui H.; Hensleigh R.; Wang R.; Brozena A.H.; Xu Z.; Dai J.; Pei Y.; Zheng C.; Pastel G.; Gao J.; Wang X.; Wang H.; Zhao J.-C.; Yang B.; Zheng X.; Luo J.; Mo Y.; Dunn B.; Hu L.
 收藏  |  浏览/下载:36/0  |  提交时间:2020/07/28 electrolyte ceramics chemical composition computer system electrolyte heating mechanical property radiative transfer sinter volatile element Article ceramics chemical structure high temperature procedures high throughput screening materials testing priority journal radiation solid state synthesis ultrafast high temperature sintering |
| Old carbon reservoirs were not important in the deglacial methane budget 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: Dyonisius M.N.; Petrenko V.V.; Smith A.M.; Hua Q.; Yang B.; Schmitt J.; Beck J.; Seth B.; Bock M.; Hmiel B.; Vimont I.; Menking J.A.; Shackleton S.A.; Baggenstos D.; Bauska T.K.; Rhodes R.H.; Sperlich P.; Beaudette R.; Harth C.; Kalk M.; Brook E.J.; Fischer H.; Severinghaus J.P.; Weiss R.F.
 收藏  |  浏览/下载:242/0  |  提交时间:2020/07/28 carbon carbon 14 carbon dioxide carbon monoxide deuterium hydrocarbon hydrogen methane nitrogen oxide biomass burning carbon deglaciation global warming Holocene methane permafrost reservoir aerosol air pollution Article atmosphere biomass carbon cycle carbon footprint deglaciation environmental temperature Holocene ice core record ice sheet lake landslide moisture permafrost priority journal sediment soil thawing |
| Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations 期刊论文 , 2020, 卷号: 367, 期号: 6478 作者: Wilmes S.; Hafer M.; Vuorio J.; Tucker J.A.; Winkelmann H.; Löchte S.; Stanly T.A.; Pulgar Prieto K.D.; Poojari C.; Sharma V.; Richter C.P.; Kurre R.; Hubbard S.R.; Christopher Garcia K.; Moraga I.; Vattulainen I.; Hitchcock I.S.; Piehler J.
 收藏  |  浏览/下载:49/0  |  提交时间:2020/07/28 cytokine receptor homodimer Janus kinase 2 ligand oncoprotein cancer enzyme enzyme activity membrane molecular analysis mutation protein activation analysis Article cell membrane computer model controlled study dimerization fluorescence microscopy gene mutation HeLa cell line molecular dynamics mutant oncogene priority journal protein domain protein interaction quantitative analysis signal transduction |
| Na+-gated water-conducting nanochannels for boosting CO2 conversion to liquid fuels 期刊论文 , 2020, 卷号: 367, 期号: 6478 作者: Li H.; Qiu C.; Ren S.; Dong Q.; Zhang S.; Zhou F.; Liang X.; Wang J.; Li S.; Yu M.
 收藏  |  浏览/下载:45/0  |  提交时间:2020/07/28 aluminum carbon dioxide carbon monoxide copper fuel hydrogen methanol nanochannel sodium ion water zeolite zinc carbon dioxide high temperature hydraulic conductivity membrane nanocomposite nanotechnology separation sodium thermodynamics adsorption Article Brunauer Emmett Teller catalyst chemical composition controlled study crystal density functional theory energy dispersive X ray spectroscopy gas hydrogenation measurement priority journal scanning electron microscopy surface area water permeability |
| Ultrafast vector imaging of plasmonic skyrmion dynamics with deep subwavelength resolution 期刊论文 , 2020, 卷号: 368, 期号: 6489 作者: Davis T.J.; Janoschka D.; Dreher P.; Frank B.; Meyer zu Heringdorf F.J.; Giessen H.
 收藏  |  浏览/下载:42/0  |  提交时间:2020/07/28 electric field electromagnetic method imaging method optical method spatial resolution wavelength absorption Article controlled study electric field electromagnetism molecular stability photoelectron spectroscopy polarization priority journal solid state spatiotemporal analysis surface charge surface plasmon resonance |
| Computing cancer's weak spots 期刊论文 , 2020, 卷号: 368, 期号: 6496 作者: Khamsi R.
 收藏  |  浏览/下载:48/0  |  提交时间:2020/07/28 ruxolitinib STAT3 protein antineoplastic agent transcription factor algorithm cancer computer simulation disease treatment drug development medicine Article cancer cell cancer radiotherapy enzyme inhibition gene activity gene expression regulation gene interaction gene mutation gene repression gene targeting human laboratory test malignant neoplasm molecular dynamics nonhuman oncologist priority journal RNA sequencing algorithm genetics mutation neoplasm personalized medicine procedures systems biology Algorithms Antineoplastic Agents Humans Mutation Neoplasms Precision Medicine Systems Biology Transcription Factors |
| Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice 期刊论文 , 2020, 卷号: 368, 期号: 6491 作者: Guthrie L.M.; Soma S.; Yuan S.; Silva A.; Zulkifli M.; Snavely T.C.; Greene H.F.; Nunez E.; Lynch B.; de Ville C.; Shanbhag V.; Lopez F.R.; Acharya A.; Petris M.J.; Kim B.-E.; Gohil V.M.; Sacchettini J.C.
 收藏  |  浏览/下载:38/0  |  提交时间:2020/07/28 copper copper zinc superoxide dismutase cytochrome c oxidase dopamine beta monooxygenase elesclomol monophenol monooxygenase protein lysine 6 oxidase copper cytochrome c oxidase elesclomol hydrazine derivative copper cytochrome enzyme enzyme activity mitochondrion mortality mutation pathology rodent survival animal cell animal experiment animal model animal tissue Article cohort analysis controlled study disease severity drug mechanism Golgi complex H9c2(2-1) cell line in vivo study male Menkes syndrome mitochondrial dynamics mortality rate mouse nerve degeneration nonhuman priority journal secretory pathway survival rate animal brain cell line degenerative disease disease model drug effect genetics knockout mouse Menkes syndrome metabolism mitochondrion pathology rat transport at the cellular level Murinae Mus Animals Biological Transport Brain Cell Line Copper Copper Transporter 1 Disease Models, Animal Electron Transport Complex IV Hydrazines Male Menkes Kinky Hair Syndrome Mice Mice, Knockout Mitochondria Neurodegenerative Diseases Rats |
| Emergence of complexity in hierarchically organized chiral particles 期刊论文 , 2020, 卷号: 368, 期号: 6491 作者: Jiang W.; Qu Z.-B.; Kumar P.; Vecchio D.; Wang Y.; Ma Y.; Bahng J.H.; Bernardino K.; Gomes W.R.; Colombari F.M.; Lozada-Blanco A.; Veksler M.; Marino E.; Simon A.; Murray C.; Muniz S.R.; de Moura A.F.; Kotov N.A.
 收藏  |  浏览/下载:39/0  |  提交时间:2020/07/28 biomaterial cetrimide cysteine gold nanocomposite nanoparticle chemical property colloid complexation complexity composite ligand nanoparticle physicochemical property symmetry adsorption Article biomineralization chemical structure chirality circular dichroism coccolith enthalpy entropy ionic strength molecular weight particle size priority journal spike wave thermodynamics zeta potential Humulus |