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Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants 期刊论文
, 2020, 卷号: 368, 期号: 6488
作者:  Walton R.T.;  Christie K.A.;  Whittaker M.N.;  Kleinstiver B.P.
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/28
adenine  adenosine  CRISPR associated endonuclease Cas9  cytosine  guanosine  SpG protein  SpRY nuclease  thymine  unclassified drug  Cas9 endonuclease Streptococcus pyogenes  bacterium  enzyme activity  genetic engineering  genetic variation  genome  Article  CRISPR-CAS9 system  DNA sequence  enzyme activity  gene editing  gene targeting  genetic variability  human  mutagenesis  nonhuman  priority journal  protein engineering  protein motif  protein structure  protospacer adjacent motif  Streptococcus pyogenes  chemistry  CRISPR Cas system  enzyme specificity  gene editing  gene targeting  genetic predisposition  genetics  HEK293 cell line  procedures  protein domain  Streptococcus pyogenes  CRISPR-Associated Protein 9  CRISPR-Cas Systems  Gene Editing  Gene Targeting  Genetic Predisposition to Disease  HEK293 Cells  Humans  Mutagenesis  Protein Domains  Substrate Specificity  
Harnessing synthetic biology for kelp forest conservation(1) 期刊论文
JOURNAL OF PHYCOLOGY, 2019, 卷号: 55, 期号: 4, 页码: 745-751
作者:  Coleman, Melinda A.;  Goold, Hugh D.
收藏  |  浏览/下载：24/0  |  提交时间：2019/10/08
algal  climate change  conservation  forest  genome engineering  kelp  synthetic biology  
Plant Genome Engineering for Targeted Improvement of Crop Traits 期刊论文
FRONTIERS IN PLANT SCIENCE, 2019, 卷号: 10
作者:  Sedeek, Khalid E. M.;  Mahas, Ahmed;  Mahfouz, Magdy
收藏  |  浏览/下载：36/0  |  提交时间：2019/10/08
CRISPR/Cas systems  genome editing  genome engineering  crop improvement  climate change  food security  synthetic biology  
Impact of Climate Change on Crops Adaptation and Strategies to Tackle Its Outcome: A Review 期刊论文
PLANTS-BASEL, 2019, 卷号: 8, 期号: 2
作者:  Raza, Ali;  Razzaq, Ali;  Mehmood, Sundas Saher;  Zou, Xiling;  Zhang, Xuekun;  Lv, Yan;  Xu, Jinsong
收藏  |  浏览/下载：29/0  |  提交时间：2019/10/08
crop adaptation  climate change  genetic engineering  genome wide association studies (GWAS)  marker-assisted selection (MSA)  molecular breeding  hormone responses  physiological responses