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期刊论文 [3]
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2020 [3]
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英语 [3]
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Science [3]
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Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Guthrie L.M.
;
Soma S.
;
Yuan S.
;
Silva A.
;
Zulkifli M.
;
Snavely T.C.
;
Greene H.F.
;
Nunez E.
;
Lynch B.
;
de Ville C.
;
Shanbhag V.
;
Lopez F.R.
;
Acharya A.
;
Petris M.J.
;
Kim B.-E.
;
Gohil V.M.
;
Sacchettini J.C.
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/28
copper
copper zinc superoxide dismutase
cytochrome c oxidase
dopamine beta monooxygenase
elesclomol
monophenol monooxygenase
protein lysine 6 oxidase
copper
cytochrome c oxidase
elesclomol
hydrazine derivative
copper
cytochrome
enzyme
enzyme activity
mitochondrion
mortality
mutation
pathology
rodent
survival
animal cell
animal experiment
animal model
animal tissue
Article
cohort analysis
controlled study
disease severity
drug mechanism
Golgi complex
H9c2(2-1) cell line
in vivo study
male
Menkes syndrome
mitochondrial dynamics
mortality rate
mouse
nerve degeneration
nonhuman
priority journal
secretory pathway
survival rate
animal
brain
cell line
degenerative disease
disease model
drug effect
genetics
knockout mouse
Menkes syndrome
metabolism
mitochondrion
pathology
rat
transport at the cellular level
Murinae
Mus
Animals
Biological Transport
Brain
Cell Line
Copper
Copper Transporter 1
Disease Models, Animal
Electron Transport Complex IV
Hydrazines
Male
Menkes Kinky Hair Syndrome
Mice
Mice, Knockout
Mitochondria
Neurodegenerative Diseases
Rats
Meet the psychobiome
期刊论文
, 2020, 卷号: 368, 期号: 6491
作者:
Pennisi E.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/28
4 aminobutyric acid
antibiotic agent
dopamine
kynurenine
probiotic agent
queuine
serotonin
psychotropic agent
bacterium
biome
drug
microbial activity
nervous system disorder
allergy
Alzheimer disease
antimicrobial therapy
anxiety disorder
archaeon
Article
autism
bacterium culture
Bacteroides
blood brain barrier
blood vessel
brain disease
clinical effectiveness
constipation
depression
drug use
enteroendocrine cell
enteropathy
entrepreneurship
epilepsy
fecal microbiota transplantation
feces analysis
Food and Drug Administration
fungus
genomics
human
insomnia
intestine flora
irritable colon
mammal cell
microbiology
microbiome
nerve cell
nervous system
nervous system development
neurologic disease
nonhuman
obesity
pain threshold
Parkinson disease
physician
priority journal
psychobiome
psychological aspect
psychological well-being
schizophrenia
scientist
United States
vagus nerve
virus
animal
bacterium
chemistry
drug development
intestine flora
isolation and purification
metabolism
microbiology
physiology
procedures
Animals
Bacteria
Drug Discovery
Gastrointestinal Microbiome
Humans
Nervous System Diseases
Psychotropic Drugs
Dopamine promotes cognitive effort by biasing the benefits versus costs of cognitive work
期刊论文
, 2020, 卷号: 367, 期号: 6484
作者:
Westbrook A.
;
van den Bosch R.
;
Määttä J.I.
;
Hofmans L.
;
Papadopetraki D.
;
Cools R.
;
Frank M.J.
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/28
dopamine
dopamine 2 receptor
methylphenidate
sulpiride
dopamine
dopamine 2 receptor blocking agent
dopamine uptake inhibitor
brain
cost-benefit analysis
decision making
hormone
sampling
adult
Article
cognition
cost benefit analysis
decision making
dopamine metabolism
female
gaze
human
human experiment
male
memory consolidation
motivation
normal human
priority journal
receptor blocking
striate cortex
task performance
adolescent
biosynthesis
caudate nucleus
cognition
corpus striatum
drug effect
eye fixation
memory
metabolism
reward
saccadic eye movement
signal transduction
young adult
Adolescent
Caudate Nucleus
Choice Behavior
Cognition
Corpus Striatum
Decision Making
Dopamine
Dopamine D2 Receptor Antagonists
Dopamine Uptake Inhibitors
Female
Fixation, Ocular
Humans
Male
Memory
Methylphenidate
Motivation
Reward
Saccades
Signal Transduction
Sulpiride
Young Adult