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The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319
作者:  Wang, Shanshan;  Ye, Fei;  Ren, Qingjia;  Sun, Shengnan;  Xia, Weina;  Wang, Zhuwei;  Guo, Haolin;  Li, Han;  Zhang, Shujing;  Lowe, Scott;  Chen, Meng;  Du, Qinghong;  Li, Weihong
收藏  |  浏览/下载：29/0  |  提交时间：2024/03/01
Tibetan medicine  Qiwei tiexie capsule  Liver fibrosis  Inflammation  NLRP3 inflammasome  
TLR2 inhibition ameliorates the amplification effect of LPS on lipid accumulation and lipotoxicity in hepatic cells 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9, 期号: 18
作者:  Zhang, Liting;  Xie, Zehui;  Yu, Hongmiao;  Du, Haoxuan;  Wang, Xuqiao;  Cai, Jiazheng;  Qiu, Yingfei;  Chen, Rui;  Jiang, Xiaofeng;  Liu, Zelin;  Li, Yi;  Chen, Tuo
收藏  |  浏览/下载：34/0  |  提交时间：2022/04/28
FATTY LIVER-DISEASE  NONALCOHOLIC STEATOHEPATITIS  ADVANCED FIBROSIS  LIPOPOLYSACCHARIDE  RECEPTORS  AXIS  ACID  
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis 期刊论文
, 2020, 卷号: 367, 期号: 6478
作者:  Zhao P.;  Sun X.;  Chaggan C.;  Liao Z.;  Wong K.I.;  He F.;  Singh S.;  Loomba R.;  Karin M.;  Witztum J.L.;  Saltiel A.R.
收藏  |  浏览/下载：65/0  |  提交时间：2020/07/28
6,7 dihydro 4 hydroxy 3 (2' hydroxy 1,1' biphenyl 4 yl) 6 oxothieno[2,3 b]pyridine 5 carbonitrile  adenosine phosphate  caspase 3  caspase 6  caspase 7  cytochrome c  hydroxymethylglutaryl coenzyme A reductase kinase  matrix metalloproteinase  apoptosis  cytochrome  enzyme  enzyme activity  inhibition  protein  rodent  AMPK signaling  animal experiment  animal model  animal tissue  apoptosis  Article  C57BL 6 mouse  cell death  controlled study  drug mechanism  enzyme activation  enzyme activity  enzyme inhibition  enzyme phosphorylation  enzyme repression  gene knockout  human  human cell  human tissue  liver cell  liver fibrosis  liver injury  male  mouse  nonalcoholic steatohepatitis  nonhuman  priority journal  protein cleavage  protein secretion