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Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays 期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:  Mahapatra, Debabrata;  Franzosa, Jill A.;  Roell, Kyle;  Kuenemann, Melaine Agnes;  Houck, Keith A.;  Reif, David M.;  Fourches, Denis;  Kullman, Seth W.
收藏  |  浏览/下载:43/0  |  提交时间:2019/05/04
Use of High-Throughput In Vitro Toxicity Screening Data in Cancer Hazard Evaluations by IARC Monograph Working Groups 期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2018, 卷号: 35, 期号: 1, 页码: 51-64
作者:  Chiu, Weihsueh A.;  Guyton, Kathryn Z.;  Martin, Matthew T.;  Reif, David M.;  Rusyn, Ivan
收藏  |  浏览/下载:19/0  |  提交时间:2019/05/04
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 152, 期号: 2, 页码: 323-339
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Richard, Ann M.;  Knudsen, Thomas B.;  Shah, Imran;  Little, Stephen;  Wambaugh, John;  Setzer, R. Woodrow;  Kothya, Parth;  Phuong, Jimmy;  Filer, Dayne;  Smith, Doris;  Reif, David;  Rotroff, Daniel;  Kleinstreuer, Nicole;  Sipes, Nisha;  Xia, Menghang;  Huang, Ruili;  Crofton, Kevin;  Thomas, Russell S.
收藏  |  浏览/下载:47/0  |  提交时间:2019/05/04
Using ToxCast (TM) Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 7, 页码: 910-919
作者:  Shah, Imran;  Setzer, R. Woodrow;  Jack, John;  Houck, Keith A.;  Judson, Richard S.;  Knudsen, Thomas B.;  Liu, Jie;  Martin, Matthew T.;  Reif, David M.;  Richard, Ann M.;  Thomas, Russell S.;  Crofton, Kevin M.;  Dix, David J.;  Kavlock, Robert J.
收藏  |  浏览/下载:33/0  |  提交时间:2019/05/04
Advancing Toxicology Research Using In Vivo High Throughput Toxicology with Small Fish Models 期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2016, 卷号: 33, 期号: 4, 页码: 435-452
作者:  Planchart, Antonio;  Mattingly, Carolyn J.;  Allen, David;  Ceger, Patricia;  Casey, Warren;  Hinton, David;  Kanungo, Jyotshna;  Kullman, Seth W.;  Tal, Tamara;  Bondesson, Maria;  Burgess, Shawn M.;  Sullivan, Con;  Kim, Carol;  Behl, Mamta;  Padilla, Stephanie;  Reif, David M.;  Tanguay, Robert L.;  Hamm, Jon
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04
Data-Driven Asthma Endotypes Defined from Blood Biomarker and Gene Expression Data 期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 2
作者:  George, Barbara Jane;  Reif, David M.;  Gallagher, Jane E.;  Williams-DeVane, ClarLynda R.;  Heidenfelder, Brooke L.;  Hudgens, Edward E.;  Jones, Wendell;  Neas, Lucas;  Hubal, Elaine A. Cohen;  Edwards, Stephen W.
收藏  |  浏览/下载:42/0  |  提交时间:2019/05/04
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2014, 卷号: 48, 期号: 15, 页码: 8706-8716
作者:  Rotroff, Daniel M.;  Martin, Matt T.;  Dix, David J.;  Filer, Dayne L.;  Houck, Keith A.;  Knudsen, Thomas B.;  Sipes, Nisha S.;  Reif, David M.;  Xia, Menghang;  Huang, Ruili;  Judson, Richard S.
收藏  |  浏览/下载:48/0  |  提交时间:2019/05/04
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway 期刊论文
SCIENTIFIC REPORTS, 2014, 卷号: 4
作者:  Huang, Ruili;  Sakamuru, Srilatha;  Martin, Matt T.;  Reif, David M.;  Judson, Richard S.;  Houck, Keith A.;  Casey, Warren;  Hsieh, Jui-Hua;  Shockley, Keith R.;  Ceger, Patricia;  Fostel, Jennifer;  Witt, Kristine L.;  Tong, Weida;  Rotroff, Daniel M.;  Zhao, Tongan;  Shinn, Paul;  Simeonov, Anton;  Dix, David J.;  Austin, Christopher P.;  Kavlock, Robert J.;  Tice, Raymond R.;  Xia, Menghang
收藏  |  浏览/下载:50/0  |  提交时间:2019/05/04
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms 期刊论文
NATURE BIOTECHNOLOGY, 2014, 卷号: 32, 期号: 6, 页码: 583-+
作者:  Kleinstreuer, Nicole C.;  Yang, Jian;  Berg, Ellen L.;  Knudsen, Thomas B.;  Richard, Ann M.;  Martin, Matthew T.;  Reif, David M.;  Judson, Richard S.;  Polokoff, Mark;  Dix, David J.;  Kavlock, Robert J.;  Houck, Keith A.
收藏  |  浏览/下载:36/0  |  提交时间:2019/05/04
Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate 期刊论文
TOXICOLOGICAL SCIENCES, 2013, 卷号: 136, 期号: 2, 页码: 308-327
作者:  Wambaugh, John F.;  Setzer, R. Woodrow;  Pitruzzello, Ann M.;  Liu, Jie;  Reif, David M.;  Kleinstreuer, Nicole C.;  Wang, Nina Ching Y.;  Sipes, Nisha;  Martin, Matthew;  Das, Kaberi;  DeWitt, Jamie C.;  Strynar, Mark;  Judson, Richard;  Houck, Keith A.;  Lau, Christopher
收藏  |  浏览/下载:27/0  |  提交时间:2019/05/04