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| Mechanistic basis for ubiquitin modulation of a protein energy landscape 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 12
作者: Carroll E.C.; Latorraca N.R.; Lindner J.M.; Maguire B.C.; Pelton J.G.; Marqusee S.
  收藏 | 浏览/下载：13/0 | 提交时间：2021/05/24 |
| Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者: Wingler L.M.; Skiba M.A.; McMahon C.; Staus D.P.; Kleinhenz A.L.W.; Suomivuori C.-M.; Latorraca N.R.; Dror R.O.; Lefkowitz R.J.; Kruse A.C.
收藏 | 浏览/下载：36/0 | 提交时间：2020/07/28
angiotensin 1 receptor beta arrestin G protein coupled receptor biochemistry crystal chemistry crystal structure physiological response protein signaling allosterism alpha helix amino terminal sequence Article binding affinity binding site carboxy terminal sequence conformational transition crystallization hydrogen bond molecular dynamics priority journal protein binding protein conformation protein protein interaction protein stability signal transduction thermostability |
| Molecular mechanism of biased signaling in a prototypical G protein-coupled receptor 期刊论文
, 2020, 卷号: 367, 期号: 6480
作者: Suomivuori C.-M.; Latorraca N.R.; Wingler L.M.; Eismann S.; King M.C.; Kleinhenz A.L.W.; Skiba M.A.; Staus D.P.; Kruse A.C.; Lefkowitz R.J.; Dror R.O.
收藏 | 浏览/下载：25/0 | 提交时间：2020/07/28
angiotensin 1 receptor beta arrestin 1 beta arrestin 2 G protein coupled receptor rhodopsin chemical binding design method ligand molecular analysis protein signaling allosterism Article carboxy terminal sequence conformational transition controlled study crystal structure human ligand binding molecular dynamics priority journal protein conformation signal transduction structural model |
| Diverse GPCRs exhibit conserved water networks for stabilization and activation 期刊论文
Proceedings of the National Academy of Sciences of the United States of America, 2019, 卷号: 116, 期号: 8
作者: Venkatakrishnan A.J.; Ma A.K.; Fonseca R.; Latorraca N.R.; Kelly B.; Betz R.M.; Asawa C.; Kobilka B.K.; Dror R.O.
收藏 | 浏览/下载：198/0 | 提交时间：2021/01/06 |
