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| Study at Molecular Level Finds Indian River Lagoon Green Sea Turtles Biologically Stressed 科技资讯 2021 收藏  |  浏览/下载:0/0  |  提交时间:2021/10/13 |
| Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling 期刊论文 Science, 2021, 卷号: 372, 期号: 6537 作者: Weber E.W.; Parker K.R.; Sotillo E.; Lynn R.C.; Anbunathan H.; Lattin J.; Good Z.; Belk J.A.; Daniel B.; Klysz D.; Malipatlolla M.; Xu P.; Bashti M.; Heitzeneder S.; Labanieh L.; Vandris P.; Majzner R.G.; Qi Y.; Sandor K.; Chen L.-C.; Prabhu S.; Gentles A.J.; Wandless T.J.; Satpathy A.T.; Chang H.Y.; Mackall C.L. 收藏  |  浏览/下载:22/0  |  提交时间:2022/01/14 |
| Signatures of immune dysfunction in HIV and HCV infection share features with chronic inflammation in aging and persist after viral reduction or elimination 期刊论文 Proceedings of the National Academy of Sciences of the United States of America, 2021, 卷号: 118, 期号: 14 作者: Lopez Angel C.J.; Pham E.A.; Du H.; Vallania F.; Fram B.J.; Perez K.; Nguyen T.; Rosenberg-Hasson Y.; Ahmed A.; Dekker C.L.; Grant P.M.; Khatri P.; Maecker H.T.; Glenn J.S.; Davis M.M.; Furman D. 收藏  |  浏览/下载:20/0  |  提交时间:2021/05/24 |
| Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications 期刊论文 Science, 2020, 卷号: 369, 期号: 6508 作者: Mathew D.; Giles J.R.; Baxter A.E.; Oldridge D.A.; Greenplate A.R.; Wu J.E.; Alanio C.; Kuri-Cervantes H.; Pampena M.B.; D'Andrea K.; Manne S.; Chen Z.; Huang Y.J.; Reilly J.P.; Weisman A.R.; Ittner C.A.G.; Kuthuru O.; Dougherty J.; Nzingha K.; Han N.; Kim J.; Pattekar A.; Goodwin E.C.; Anderson E.M.; Weirick M.E.; Gouma S.; Arevalo C.P.; Bolton M.J.; Chen F.; Lacey S.F.; Ramage H.; Cherry S.; Hensley S.E.; Apostolidis S.A.; Huang A.C.; Vella L.A.; Betts M.R.; Meyer N.J.; Wherry E.J.; Alam Z.; Addison M.M.; Byrne K.T.; Chandra A.; Descamps H.C.; Kaminskiy Y.; Hamilton J.T.; Noll J.H.; Omran D.K.; Perkey E.; Prager E.M.; Pueschl D.; Shah J.B.; Shilan J.S.; Vanderbeck A.N.; UPenn COVID Processing Unit 收藏  |  浏览/下载:21/0  |  提交时间:2022/01/14 |
| Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity 期刊论文 , 2020, 卷号: 367, 期号: 6480 作者: Wang J.; Li P.; Yu Y.; Fu Y.; Jiang H.; Lu M.; Sun Z.; Jiang S.; Lu L.; Wu M.X. 收藏  |  浏览/下载:33/0  |  提交时间:2020/07/28 2',3' cyclic guanosine monophosphate adenosine monophosphate influenza vaccine interferon nanoparticle pulmonary surfactant biomimetic nanoparticle purine nucleotide surfactant protein A surfactant protein D unclassified drug cell drug resistance immune response immunity induced response influenza nanoparticle rodent surfactant vaccine animal cell animal experiment animal model animal tissue Article CD8+ T lymphocyte cellular immunity controlled study cross protection cytokine response drug efficacy drug safety drug synthesis female human humoral immunity hydrophilicity immune response immunopathology immunosurveillance influenza innate immunity lung alveolus epithelium cell lung alveolus macrophage mouse Mustela putorius furo nanoencapsulation nonhuman priority journal Mus Mustela |
| MRNA destabilization by BTG1 and BTG2 maintains T cell quiescence 期刊论文 , 2020, 卷号: 367, 期号: 6483 作者: Hwang S.S.; Lim J.; Yu Z.; Kong P.; Sefik E.; Xu H.; Harman C.C.D.; Kim L.K.; Lee G.R.; Li H.-B.; Flavell R.A. 收藏  |  浏览/下载:24/0  |  提交时间:2020/07/28 CD69 antigen chemokine receptor CCR7 epidermal growth factor receptor 2 Hermes antigen interleukin 2 receptor alpha interleukin 2 receptor gamma interleukin 7 receptor kruppel like factor 2 messenger RNA polyadenylic acid T lymphocyte receptor transcription factor FKHR transcriptome biodegradation cell component RNA adenylation Article BTG1 gene BTG2 gene Ccr7 gene CD4+ T lymphocyte CD8+ T lymphocyte cell differentiation cell expansion cell maturation cell migration cell proliferation cell size cell specificity cell survival controlled study CRISPR-CAS9 system flow cytometry gene gene control gene expression gene function gene identification immunoprecipitation in vitro study in vivo study memory T lymphocyte nonhuman phylogenetic tree priority journal RNA degradation RNA sequencing S1pr1 gene Sell gene spleen T lymphocyte T lymphocyte activation tail length (comet assay) thymus upregulation |