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Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates 期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 1, 页码: 487-500
作者:  Strickland, Jenna D.;  Martin, Matthew T.;  Richard, Ann M.;  Houck, Keith A.;  Shafer, Timothy J.
收藏  |  浏览/下载:24/0  |  提交时间:2019/05/04
Recommendation on Test Readiness Criteria for New Approach Methods in Toxicology: Exemplified for Developmental Neurotoxicity 期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2018, 卷号: 35, 期号: 3, 页码: 306-352
作者:  Bal-Price, Anna;  Hogberg, Helena T.;  Crofton, Kevin M.;  Daneshian, Mardas;  FitzGerald, Rex E.;  Fritsche, Ellen;  Heinonen, Tuula;  Bennekou, Susanne Hougaard;  Klima, Stefanie;  Piersma, Aldert H.;  Sachana, Magdalini;  Shafer, Timothy J.;  Terron, Andrea;  Monnet-Tschudi, Florianne;  Viviani, Barbara;  Waldmann, Tanja;  Westerink, Remco H. S.;  Wilks, Martin F.;  Witters, Hilda;  Zurich, Marie-Gabrielle;  Leist, Marcel
收藏  |  浏览/下载:50/0  |  提交时间:2019/05/04
Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays 期刊论文
NEUROTOXICOLOGY, 2017, 卷号: 60, 页码: 234-239
作者:  Johnstone, Andrew F. M.;  Strickland, Jenna D.;  Crofton, Kevin M.;  Gennings, Chris;  Shafer, Timothy J.
收藏  |  浏览/下载:24/0  |  提交时间:2019/05/04
A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing 期刊论文
NEUROTOXICOLOGY, 2017, 卷号: 60, 页码: 280-292
作者:  Vassallo, Andrea;  Chiappalone, Michela;  Lopes, Ricardo De Camargos;  Scelfo, Bibiana;  Novellino, Antonio;  Defranchi, Enrico;  Palosaari, Taina;  Weisschu, Timo;  Ramirez, Tzutzuy;  Martinoia, Sergio;  Johnstone, Andrew F. M.;  Mack, Cina M.;  Landsiedel, Robert;  Whelan, Maurice;  Bal-Price, Anna;  Shafer, Timothy J.
收藏  |  浏览/下载:38/0  |  提交时间:2019/05/04
Expanding the test set: Chemicals with potential to disrupt mammalian brain development 期刊论文
NEUROTOXICOLOGY AND TERATOLOGY, 2015, 卷号: 52, 页码: 25-35
作者:  Mundy, William R.;  Padilla, Stephanie;  Breier, Joseph M.;  Crofton, Kevin M.;  Gilbert, Mary E.;  Herr, David W.;  Jensen, Karl F.;  Radio, Nicholas M.;  Raffaele, Kathleen C.;  Schumacher, Kelly;  Shafer, Timothy J.;  Cowden, John
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
Sensitivity of neuroprogenitor cells to chemical-induced apoptosis using a multiplexed assay suitable for high-throughput screening 期刊论文
TOXICOLOGY, 2015, 卷号: 333, 页码: 14-24
作者:  Druwe, Ingrid;  Freudenrich, Theresa M.;  Wallace, Kathleen;  Shafer, Timothy J.;  Mundy, William R.
收藏  |  浏览/下载:26/0  |  提交时间:2019/05/04
Improving in vitro to in vivo extrapolation by incorporating toxicokinetic measurements: A case study of lindane-induced neurotoxicity 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2015, 卷号: 283, 期号: 1, 页码: 9-19
作者:  Croom, Edward L.;  Shafer, Timothy J.;  Evans, Marina V.;  Mundy, William R.;  Eklund, Chris R.;  Johnstone, Andrew F. M.;  Mack, Cina M.;  Pegram, Rex A.
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04
Putative adverse outcome pathways relevant to neurotoxicity 期刊论文
CRITICAL REVIEWS IN TOXICOLOGY, 2015, 卷号: 45, 期号: 1, 页码: 83-91
作者:  Bal-Price, Anna;  Crofton, Kevin M.;  Sachana, Magdalini;  Shafer, Timothy J.;  Behl, Mamta;  Forsby, Anna;  Hargreaves, Alan;  Landesmann, Brigitte;  Lein, Pamela J.;  Louisse, Jochem;  Monnet-Tschudi, Florianne;  Paini, Alicia;  Rolaki, Alexandra;  Schrattenholz, Andre;  Sunol, Cristina;  van Thriel, Christoph;  Whelan, Maurice;  Fritsche, Ellen
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
Glufosinate binds N-methyl-D-aspartate receptors and increases neuronal network activity in vitro 期刊论文
NEUROTOXICOLOGY, 2014, 卷号: 45, 页码: 38-47
作者:  Lantz, Stephen R.;  Mack, Cina M.;  Wallace, Kathleen;  Key, Ellen F.;  Shafer, Timothy J.;  Casida, John E.
收藏  |  浏览/下载:25/0  |  提交时间:2019/05/04
Burst and principal components analyses of MEA data for 16 chemicals describe at least three effects classes 期刊论文
NEUROTOXICOLOGY, 2014, 卷号: 40, 页码: 75-85
作者:  Mack, Cina M.;  Lin, Bryant J.;  Turner, James D.;  Johnstone, Andrew F. M.;  Burgoon, Lyle D.;  Shafer, Timothy J.
收藏  |  浏览/下载:27/0  |  提交时间:2019/05/04