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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2018, 卷号: 126, 期号: 7
作者:  Xia, Menghang;  Huang, Ruili;  Shi, Qiang;  Boyd, Windy A.;  Zhao, Jinghua;  Sun, Nuo;  Rice, Julie R.;  Dunlap, Paul E.;  Hackstadt, Amber J.;  Bridge, Matt F.;  Smith, Marjolein V.;  Dai, Sheng;  Zheng, Wei;  Chu, Pei-Hsuan;  Gerhold, David;  Witt, Kristine L.;  DeVito, Michael;  Freedman, Jonathan H.;  Austin, Christopher P.;  Houck, Keith A.;  Thomas, Russell S.;  Paules, Richard S.;  Tice, Raymond R.;  Simeonov, Anton
收藏  |  浏览/下载:57/0  |  提交时间:2019/05/04
Accelerating the Pace of Chemical Risk Assessment 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2018, 卷号: 31, 期号: 5, 页码: 287-290
作者:  Kavlock, Robert J.;  Bahadori, Tina;  Barton-Maclaren, Tara S.;  Gwinn, Maureen R.;  Rasenberg, Mike;  Thomas, Russell S.
收藏  |  浏览/下载:28/0  |  提交时间:2019/05/04
Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 163, 期号: 1, 页码: 152-169
作者:  Wambaugh, John F.;  Hughes, Michael F.;  Ring, Caroline L.;  MacMillan, Denise K.;  Ford, Jermaine;  Fennell, Timothy R.;  Black, Sherry R.;  Snyder, Rodney W.;  Sipes, Nisha S.;  Wetmore, Barbara A.;  Westerhout, Joost;  Setzer, R. Woodrow;  Pearce, Robert G.;  Simmons, Jane Ellen;  Thomas, Russell S.
收藏  |  浏览/下载:30/0  |  提交时间:2019/05/04
The US Federal Tox21 Program: A Strategic and Operational Plan for Continued Leadership 期刊论文
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2018, 卷号: 35, 期号: 2, 页码: 163-168
作者:  Thomas, Russell S.;  Paules, Richard S.;  Simeonov, Anton;  Fitzpatrick, Suzanne C.;  Crofton, Kevin M.;  Casey, Warren M.;  Mendrick, Donna L.
收藏  |  浏览/下载:25/0  |  提交时间:2019/05/04
Predicting Organ Toxicity Using &ITin Vitro&IT Bioactivity Data and Chemical Structure 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2017, 卷号: 30, 期号: 11, 页码: 2046-2059
作者:  Liu, Jie;  Patlewicz, Grace;  Williams, Antony J.;  Thomas, Russell S.;  Shah, Imran
收藏  |  浏览/下载:1/0  |  提交时间:2019/05/04
Application of Gene Set Enrichment Analysis for Identification of Chemically Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk Assessment 期刊论文
TOXICOLOGICAL SCIENCES, 2017, 卷号: 157, 期号: 1, 页码: 85-99
作者:  Dean, Jeffry L.;  Zhao, Q. Jay;  Lambert, Jason C.;  Hawkins, Belinda S.;  Thomas, Russell S.;  Wesselkamper, Scott C.
收藏  |  浏览/下载:35/0  |  提交时间:2019/05/04
Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 152, 期号: 2, 页码: 323-339
作者:  Judson, Richard;  Houck, Keith;  Martin, Matt;  Richard, Ann M.;  Knudsen, Thomas B.;  Shah, Imran;  Little, Stephen;  Wambaugh, John;  Setzer, R. Woodrow;  Kothya, Parth;  Phuong, Jimmy;  Filer, Dayne;  Smith, Doris;  Reif, David;  Rotroff, Daniel;  Kleinstreuer, Nicole;  Sipes, Nisha;  Xia, Menghang;  Huang, Ruili;  Crofton, Kevin;  Thomas, Russell S.
收藏  |  浏览/下载:34/0  |  提交时间:2019/05/04
ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 8, 页码: 1225-1251
作者:  Richard, Ann M.;  Judson, Richard S.;  Houck, Keith A.;  Grulke, Christopher M.;  Volarath, Patra;  Thillainadarajah, Inthirany;  Yang, Chihae;  Rathman, James;  Martin, Matthew T.;  Wambaugh, John F.;  Knudsen, Thomas B.;  Kancherla, Jayaram;  Mansouri, Kamel;  Patlewicz, Grace;  Williams, Antony J.;  Little, Stephen B.;  Crofton, Kevin M.;  Thomas, Russell S.
收藏  |  浏览/下载:33/0  |  提交时间:2019/05/04
Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2016, 卷号: 79, 页码: 12-24
作者:  Shah, Imran;  Liu, Jie;  Judson, Richard S.;  Thomas, Russell S.;  Patlewicz, Grace
收藏  |  浏览/下载:2/0  |  提交时间:2019/05/04
Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing 期刊论文
TOXICOLOGICAL SCIENCES, 2015, 卷号: 148, 期号: 1, 页码: 121-136
作者:  Wetmore, Barbara A.;  Wambaugh, John F.;  Allen, Brittany;  Ferguson, Stephen S.;  Sochaski, Mark A.;  Setzer, R. Woodrow;  Houck, Keith A.;  Strope, Cory L.;  Cantwell, Katherine;  Judson, Richard S.;  LeCluyse, Edward;  Clewell, Harvey J.;  Thomas, Russell S.;  Andersen, Melvin E.
收藏  |  浏览/下载:31/0  |  提交时间:2019/05/04