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Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making 期刊论文
TOXICOLOGICAL SCIENCES, 2018, 卷号: 162, 期号: 2, 页码: 341-348
作者:  Tan, Yu-Mei;  Worley, Rachel R.;  Leonard, Jeremy A.;  Fisher, Jeffrey W.
收藏  |  浏览/下载:23/0  |  提交时间:2019/05/04
Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications 期刊论文
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2017, 卷号: 90, 页码: 104-115
作者:  Paini, Alicia;  Leonard, Jeremy A.;  Kliment, Tomas;  Tan, Yu-Mei;  Worth, Andrew
收藏  |  浏览/下载:55/0  |  提交时间:2019/05/04
Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates 期刊论文
CHEMOSPHERE, 2017, 卷号: 184, 页码: 1194-1201
作者:  Moreau, Marjory;  Leonard, Jeremy;  Phillips, Katherine A.;  Campbell, Jerry;  Pendse, Salil N.;  Nicolas, Chantel;  Phillips, Martin;  Yoon, Miyoung;  Tan, Yu-Mei;  Smith, Sherrie;  Pudukodu, Harish;  Isaacs, Kristin;  Clewell, Harvey
收藏  |  浏览/下载:45/0  |  提交时间:2019/05/04
From the exposome to mechanistic understanding of chemical-induced adverse effects 期刊论文
ENVIRONMENT INTERNATIONAL, 2017, 卷号: 99, 页码: 97-106
作者:  Escher, Beate I.;  Hackermuller, Joerg;  Polte, Tobias;  Scholz, Stefan;  Aigner, Achim;  Altenburger, Rolf;  Boehme, Alexander;  Bopp, Stephanie K.;  Brack, Werner;  Busch, Wibke;  Chadeau-Hyam, Marc;  Covaci, Adrian;  Eisentraeger, Adolf;  Galligan, James J.;  Garcia-Reyero, Natalia;  Hartung, Thomas;  Hein, Michaela;  Herberth, Gunda;  Jahnke, Annika;  Kleinjans, Jos;  Kluever, Nils;  Krauss, Martin;  Lamoree, Marja;  Lehmann, Irina;  Luckenbach, Till;  Miller, Gary W.;  Mueller, Andrea;  Phillips, David H.;  Reemtsma, Thorsten;  Rolle-Kampczyk, Ulrike;  Schueuermann, Gerrit;  Schwikowski, Benno;  Tan, Yu-Mei;  Trump, Saskia;  Walter-Rohde, Susanne;  Wambaugh, John F.
收藏  |  浏览/下载:45/0  |  提交时间:2019/05/04
Conceptual Framework To Extend Life Cycle Assessment Using Near Field Human Exposure Modeling and High-Throughput Tools for Chemicals 期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 卷号: 50, 期号: 21, 页码: 11922-11934
作者:  Csiszar, Susan A.;  Meyer, David E.;  Dionisio, Kathie L.;  Egeghy, Peter;  Isaacs, Kristin K.;  Price, Paul S.;  Scanlon, Kelly A.;  Tan, Yu-Mei;  Thomas, Kent;  Vallero, Daniel;  Bare, Jane C.
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/04
Use of PBPK models in risk assessment of agrochemicals 期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 卷号: 252
作者:  Lowit, Anna;  Tan, Yu-Mei;  Holman, Elizabeth
收藏  |  浏览/下载:11/0  |  提交时间:2019/05/04
Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling 期刊论文
TOXICOLOGICAL SCIENCES, 2016, 卷号: 151, 期号: 1, 页码: 57-70
作者:  Leonard, Jeremy A.;  Tan, Yu-Mei;  Gilbert, Mary;  Isaacs, Kristin;  El-Masri, Hisham
收藏  |  浏览/下载:14/0  |  提交时间:2019/05/04
Adverse Outcome Pathways-Organizing Toxicological Information to Improve Decision Making 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2016, 卷号: 356, 期号: 1, 页码: 170-181
作者:  Edwards, Stephen W.;  Tan, Yu-Mei;  Villeneuve, Daniel L.;  Meek, M. E.;  McQueen, Charlene A.
收藏  |  浏览/下载:27/0  |  提交时间:2019/05/04
A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 卷号: 124, 期号: 1, 页码: 53-60
作者:  Phillips, Martin B.;  Leonard, Jeremy A.;  Grulke, Christopher M.;  Chang, Daniel T.;  Edwards, Stephen W.;  Brooks, Raina;  Goldsmith, Michael-Rock;  El-Masri, Hisham;  Tan, Yu-Mei
收藏  |  浏览/下载:28/0  |  提交时间:2019/05/04
Uses of NHANES Biomarker Data for Chemical Risk Assessment: Trends, Challenges, and Opportunities 期刊论文
ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 卷号: 123, 期号: 10, 页码: 919-927
作者:  Sobus, Jon R.;  DeWoskin, Robert S.;  Tan, Yu-Mei;  Pleil, Joachim D.;  Phillips, Martin Blake;  George, Barbara Jane;  Christensen, Krista;  Schreinemachers, Dina M.;  Williams, Marc A.;  Hubal, Elaine A. Cohen;  Edwards, Stephen W.
收藏  |  浏览/下载:17/0  |  提交时间:2019/05/04