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DOI10.1186/s12891-019-2662-5
Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial
Bennell, Kim L.1; Nelligan, Rachel K.1; Kimp, Alexander J.1; Wrigley, Tim V.1; Metcalf, Ben1; Kasza, Jessica2; Hodges, Paul W.3; Hinman, Rana S.1
发表日期2019
ISSN1471-2474
卷号20
英文摘要

BackgroundClinical guidelines recommend exercise as a core treatment for individuals with knee osteoarthritis (OA). However, the best type of exercise for clinical benefits is not clear, particularly in different OA subgroups. Obesity is a common co-morbidity in people with knee OA. There is some evidence suggesting that non-weight bearing exercise may be more effective than weight bearing exercise in patients with medial knee OA and obesity.MethodsTo compare the efficacy of two different exercise programs (weight bearing functional exercise and non-weight bearing quadriceps strengthening) on pain and physical function for people 50years with painful medial knee OA and obesity (body mass index 30kg/m(2)) 128 people in Melbourne, Australia will be recruited for a two group parallel-design, assessor- and participant-blinded randomised controlled trial. Participants will be randomly allocated to undertake a program of either weight bearing functional exercise or non-weight bearing quadriceps strengthening exercise. Both groups will attend five individual sessions with a physiotherapist who will teach, monitor and progress the exercise program. Participants will be asked to perform the exercises at home four times per week for 12weeks. Outcomes will be measured at baseline and 12weeks. Primary outcomes are self-reported knee pain and physical function. Secondary outcomes include other measures of knee pain, physical function, quality-of-life, participant-perceived global change, physical performance, and lower limb muscle strength.DiscussionThis study will compare the efficacy of two different 12-week physiotherapist-prescribed, home-based exercise programs for people with medial knee OA and obesity. Findings will provide valuable information to help inform exercise prescription in this common OA patient subgroup.Trial registrationAustralian New Zealand Clinical Trials Registry reference: ACTRN12617001013358, 14/7/2017


WOS研究方向Orthopedics ; Rheumatology
来源期刊BMC MUSCULOSKELETAL DISORDERS
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/99198
作者单位1.Univ Melbourne, Ctr Hlth Exercise & Sports Med, Dept Physiotherapy, Sch Hlth Sci, Melbourne, Vic, Australia;
2.Monash Univ Melbourne, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia;
3.Univ Queensland, Ctr Clin Res Excellence Spinal Pain Injury & Hlth, Sch Hlth & Rehabil Sci, Brisbane, Qld, Australia
推荐引用方式
GB/T 7714
Bennell, Kim L.,Nelligan, Rachel K.,Kimp, Alexander J.,et al. Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial[J],2019,20.
APA Bennell, Kim L..,Nelligan, Rachel K..,Kimp, Alexander J..,Wrigley, Tim V..,Metcalf, Ben.,...&Hinman, Rana S..(2019).Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial.BMC MUSCULOSKELETAL DISORDERS,20.
MLA Bennell, Kim L.,et al."Comparison of weight bearing functional exercise and non-weight bearing quadriceps strengthening exercise on pain and function for people with knee osteoarthritis and obesity: protocol for the TARGET randomised controlled trial".BMC MUSCULOSKELETAL DISORDERS 20(2019).
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