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DOI | 10.1080/09291016.2018.1464638 |
Summer season induced heat stress impact on the expression patterns of different toll-like receptor genes in Malabari goats | |
Vandana, G. D.1,2,3; Bagath, M.1; Sejian, V.1; Krishnan, G.1; Beena, V.3; Bhatta, R.1 | |
发表日期 | 2019 |
ISSN | 0929-1016 |
EISSN | 1744-4179 |
卷号 | 50期号:3页码:466-482 |
英文摘要 | The study was conducted with the primary objective of establishing the impact of heat stress on the expression pattern of different toll-like-receptors (TLRs) in Malabari goats. The study was conducted for a period of 45 days using twelve Malabari goats. The goats were randomly allocated into two groups: MC (n = 6; Malabari control) and MHS (n = 6; Malabari heat stress). At the end of study, all 12 animals were slaughtered and their mesenteric lymph node (MLN) tissues were collected for gene expression. Heat stress significantly (p < 0.05) down regulated TLR1, TLR4, TLR5 and TLR6 and significantly increased (p < 0.05) TLR2 expression pattern. A negative correlation (p < 0.01) was also established between THI and different TLRs except TLR3, TLR7 and TLR10. The study indicated that TLR2 could serve as ideal immunological marker for establishing the superior thermo-tolerance ability of Malabari breed in terms of maintaining the immune status during heat stress challenges. |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Physiology |
来源期刊 | BIOLOGICAL RHYTHM RESEARCH
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文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/97655 |
作者单位 | 1.ICAR Natl Inst Anim Nutr & Physiol, Anim Physiol Div, Bangalore, Karnataka, India; 2.Kerala Agr Univ, Acad Climate Change Educ & Res, Trichur, India; 3.Kerala Vet & Anim Sci Univ, Ctr Anim Adaptat Environm & Climate Change Studie, Trichur, India |
推荐引用方式 GB/T 7714 | Vandana, G. D.,Bagath, M.,Sejian, V.,et al. Summer season induced heat stress impact on the expression patterns of different toll-like receptor genes in Malabari goats[J],2019,50(3):466-482. |
APA | Vandana, G. D.,Bagath, M.,Sejian, V.,Krishnan, G.,Beena, V.,&Bhatta, R..(2019).Summer season induced heat stress impact on the expression patterns of different toll-like receptor genes in Malabari goats.BIOLOGICAL RHYTHM RESEARCH,50(3),466-482. |
MLA | Vandana, G. D.,et al."Summer season induced heat stress impact on the expression patterns of different toll-like receptor genes in Malabari goats".BIOLOGICAL RHYTHM RESEARCH 50.3(2019):466-482. |
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