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Water temperature and the related thermal structure and stratification of a lake are very important to lake ecosystems because of their significant effects on the vertical exchanges of dissolved and particulate matter. In this study, we present high resolution, seasonal variations in water temperature at different depths of a large deep lake on the central Tibetan Plateau. The results show that Nam Co is a typical dimictic lake whose thermal stratification begins and ends in early June and early November, respectively. Increases in the water temperature during spring and the establishment of thermal stratification in the eastern small sub-basin occur approximately one month prior to the main basin which is likely caused by the different morphometry, different water transparency during spring, and the possible presence of a spring thermal bar. The Schmidt stability of the water column is directly controlled by surface water temperature. During the ice-covered period, the homogeneous water temperature exhibits a continuous increasing trend from approximately 0.5 degrees C to 3.5 degrees C. The daily mean surface water temperature of the main open lake area is highly correlated to the air temperature but shows a hysteresis effect of approximately 38 days, which shows the significant heat storage in such a large deep lake. Nam Co is a typical lake in this area in terms of its altitude, water depth and climatic conditions, so our results have broader significance for limnological and paleolimnological studies of similar lakes on the Tibetan Plateau. (C) 2019 International Association for Great Lakes Research. Published by Elsevier B.V. All rights reserved.