Climate Change Data Portal
DOI | 10.1007/s00294-018-0852-6 |
Chromatin mobility upon DNA damage: state of the art and remaining questions | |
Zimmer, Christophe1,2,3; Fabre, Emmanuelle4,5 | |
发表日期 | 2019 |
ISSN | 0172-8083 |
EISSN | 1432-0983 |
卷号 | 65期号:1页码:1-9 |
英文摘要 | Chromosome organization and chromatin mobility are central to DNA metabolism. In particular, it has been recently shown by several labs that double strand breaks (DSBs) in yeast induce a change in chromatin mobility at the site of the damage. Intriguingly, DSB also induces a global mobility of the genome, at others, potentially undamaged positions. How mobility is regulated and what are the functional outcomes of these global changes in chromatin dynamics are, however, not yet fully understood. We present the current state of knowledge in light of the recent literature and discuss some perspectives opened by these discoveries towards genome stability. |
WOS研究方向 | Genetics & Heredity |
来源期刊 | CURRENT GENETICS |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/89811 |
作者单位 | 1.Inst Pasteur, Unite Imagerie & Modelisat, 25 Rue Docteur Roux, F-75015 Paris, France; 2.CNRS, UMR 3691, Paris, France; 3.CNRS, IP, C3BI, USR 3756, Paris, France; 4.Hop St Louis, Inst Univ Hematol, Equipe Biol & Dynam Chromosomes, Paris, France; 5.Univ Paris Diderot, Sorbonne Paris Cite, IUH, INSERM,U944,CNRS,UMR 7212, Paris, France |
推荐引用方式 GB/T 7714 | Zimmer, Christophe,Fabre, Emmanuelle. Chromatin mobility upon DNA damage: state of the art and remaining questions[J],2019,65(1):1-9. |
APA | Zimmer, Christophe,&Fabre, Emmanuelle.(2019).Chromatin mobility upon DNA damage: state of the art and remaining questions.CURRENT GENETICS,65(1),1-9. |
MLA | Zimmer, Christophe,et al."Chromatin mobility upon DNA damage: state of the art and remaining questions".CURRENT GENETICS 65.1(2019):1-9. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。