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| Ultrafine Oil Aerosol Generation for Inhalation Studies | |
| 项目编号 | R827354C008 |
| John Veranth | |
| 项目主持机构 | Mississippi State University - Main Campus |
| 开始日期 | 1999-06-01 |
| 结束日期 | 2004-05-01 |
| 英文摘要 | Project Research Results Final Report 1997 1996 13 publications for this project 2 journal articles for this project Related Information Research Grants P3: Student Design Competition Research Fellowships Small Business Innovation Research (SBIR) Grantee Research Project Results Search Distribution of H+ and Trace Metals in Ultrafine Ambient Aerosol EPA Grant Number: R824791 Title: Distribution of H+ and Trace Metals in Ultrafine Ambient Aerosol Investigators: Institution:New York University Current Institution:New York University Medical Center EPA Project Officer: Chung, Serena Project Period: October 1, 1995 through September 30, 1998 Project Amount: $589,560 RFA: Air Pollutants (1995)Recipients Lists Research Category:Air Quality and Air Toxics ,Air Description: There is a growing body of epidemiological data indicatingconsistent and coherent associations between ambient particulate matter (PM) andexcess mortality and morbidity. Recent epidemiological evidence stronglysuggests that ambient particle associated acidity is more closely correlatedwith total mortality than indices of total particulate mass. In addition,evidence is accumulating to support the hypothesis that the number of ultrafineacid particles, rather than ambient mass, is an important determining factoraffecting lung injury. Over 90% of all airborne particles are generally found in nuclei less than 50nm in diameter. However, no data are currently available on the numberconcentration of acidic ambient ultrafine particles largely because there are nosuitable methods for measuring this important quantity. We propose to develop amethod to measure the number concentration of ambient acidic particles with dless than 50 nm. Ultra-thin metal film acidic particle detectors will bedeveloped and calibrated. They will form the basis for a field sampling system(FSS) for nuclei mode particles and a personal acid aerosol monitor (PAAM) forultrafine (d<100 nm) ambient acid particles. The personal monitor will besmall and lightweight designed to be worn by an individual. The FSS will bedesigned to simultaneously sample ambient acid nuclei for evaluation of themetal content since metals can provide catalytic surfaces for reactivesubstances, both in air and in the lung. They also can serve as tracers to helpidentify sources. Using an optimized prototype of a field-ready version, we will measure thedistribution of H+ and trace metals in the nuclei mode of the ambient aerosol in various representative samples of the relatively clean regional background air in Tuxedo, NY, including air masses originating in three major upwind regions in the midwest, southeast, and eastern Canada. Publications and Presentations: Publications have been submitted on this project:View all 13 publications for this project Journal Articles: Journal Articles have been submitted on this project:View all 2 journal articles for this project Supplemental Keywords: air, ambient air, atmosphere, tropospheric, exposure, particulates, epidemiology, monitoring, measurement methods, New York, NY, Region 2., RFA, Health, Scientific Discipline, Air, Geographic Area, particulate matter, Environmental Chemistry, Chemistry, Epidemiology, State, Risk Assessments, Atmospheric Sciences, International, EPA Region, ambient aerosol, particulates, fine particles, morbidity, ambient measurement methods, exposure, atmospheric transport, human exposure, lung inflammation, epidemiological studies, tropospheric ozone, Canada, mortality, Region 2, aerosols, atmospheric chemistry, metals, ultrafine particles, New York (NY) Progress and Final Reports: 1996 1997 Final ReportProject Research Results Final Report 1997 1996 13 publications for this project 2 journal articles for this project Related Information Research Grants P3: Student Design Competition Research Fellowships Small Business Innovation Research (SBIR) Grantee Research Project Results Search Distribution of H+ and Trace Metals in Ultrafine Ambient Aerosol EPA Grant Number: R824791 Title: Distribution of H+ and Trace Metals in Ultrafine Ambient Aerosol Investigators: Institution:New York University Current Institution:New York University Medical Center EPA Project Officer: Chung, Serena Project Period: October 1, 1995 through September 30, 1998 Project Amount: $589,560 RFA: Air Pollutants (1995)Recipients Lists Research Category:Air Quality and Air Toxics ,Air Description: There is a growing body of epidemiological data indicatingconsistent and coherent associations between ambient particulate matter (PM) andexcess mortality and morbidity. Recent epidemiological evidence stronglysuggests that ambient particle associated acidity is more closely correlatedwith total mortality than indices of total particulate mass. In addition,evidence is accumulating to support the hypothesis that the number of ultrafineacid particles, rather than ambient mass, is an important determining factoraffecting lung injury. Over 90% of all airborne particles are generally found in nuclei less than 50nm in diameter. However, no data are currently available on the numberconcentration of acidic ambient ultrafine particles largely because there are nosuitable methods for measuring this important quantity. We propose to develop amethod to measure the number concentration of ambient acidic particles with dless than 50 nm. Ultra-thin metal film acidic particle detectors will bedeveloped and calibrated. They will form the basis for a field sampling system(FSS) for nuclei mode particles and a personal acid aerosol monitor (PAAM) forultrafine (d<100 nm) ambient acid particles. The personal monitor will besmall and lightweight designed to be worn by an individual. The FSS will bedesigned to simultaneously sample ambient acid nuclei for evaluation of themetal content since metals can provide catalytic surfaces for reactivesubstances, both in air and in the lung. They also can serve as tracers to helpidentify sources. Using an optimized prototype of a field-ready version, we will measure thedistribution of H+ and trace metals in the nuclei mode of the ambient aerosol in various representative samples of the relatively clean regional background air in Tuxedo, NY, including air masses originating in three major upwind regions in the midwest, southeast, and eastern Canada. Publications and Presentations: Publications have been submitted on this project:View all 13 publications for this project Journal Articles: Journal Articles have been submitted on this project:View all 2 journal articles for this project Supplemental Keywords: air, ambient air, atmosphere, tropospheric, exposure, particulates, epidemiology, monitoring, measurement methods, New York, NY, Region 2., RFA, Health, Scientific Discipline, Air, Geographic Area, particulate matter, Environmental Chemistry, Chemistry, Epidemiology, State, Risk Assessments, Atmospheric Sciences, International, EPA Region, ambient aerosol, particulates, fine particles, morbidity, ambient measurement methods, exposure, atmospheric transport, human exposure, lung inflammation, epidemiological studies, tropospheric ozone, Canada, mortality, Region 2, aerosols, atmospheric chemistry, metals, ultrafine particles, New York (NY) Progress and Final Reports: 1996 1997 Final ReportProject Research Results Final Report 1997 1996 13 publications for this project 2 journal articles for this project Related Information Research Grants P3: Student Design Competition Research Fellowships Small Business Innovation Research (SBIR) Grantee Research Project Results Search Distribution of H+ and Trace Metals in Ultrafine Ambient Aerosol EPA Grant Number: R824791 Title: Distribution of H+ and Trace Metals in Ultrafine Ambient Aerosol Investigators: Institution:New York University Current Institution:New York University Medical Center EPA Project Officer: Chung, Serena Project Period: October 1, 1995 through September 30, 1998 Project Amount: $589,560 RFA: Air Pollutants (1995)Recipients Lists Research Category:Air Quality and Air Toxics ,Air Description: There is a growing body of epidemiological data indicatingconsistent and coherent associations between ambient particulate matter (PM) andexcess mortality and morbidity. Recent epidemiological evidence stronglysuggests that ambient particle associated acidity is more closely correlatedwith total mortality than indices of total particulate mass. In addition,evidence is accumulating to support the hypothesis that the number of ultrafineacid particles, rather than ambient mass, is an important determining factoraffecting lung injury. Over 90% of all airborne particles are generally found in nuclei less than 50nm in diameter. However, no data are currently available on the numberconcentration of acidic ambient ultrafine particles largely because there are nosuitable methods for measuring this important quantity. We propose to develop amethod to measure the number concentration of ambient acidic particles with dless than 50 nm. Ultra-thin metal film acidic particle detectors will bedeveloped and calibrated. They will form the basis for a field sampling system(FSS) for nuclei mode particles and a personal acid aerosol monitor (PAAM) forultrafine (d<100 nm) ambient acid particles. The personal monitor will besmall and lightweight designed to be worn by an individual. The FSS will bedesigned to simultaneously sample ambient acid nuclei for evaluation of themetal content since metals can provide catalytic surfaces for reactivesubstances, both in air and in the lung. They also can serve as tracers to helpidentify sources. Using an optimized prototype of a field-ready version, we will measure thedistribution of H+ and trace metals in the nuclei mode of the ambient aerosol in various representative samples of the relatively clean regional background air in Tuxedo, NY, including air masses originating in three major upwind regions in the midwest, southeast, and eastern Canada. |
| 英文关键词 | air;ambient air;atmosphere;tropospheric;exposure;particulates;epidemiology;monitoring;measurement methods;New York;NY;Region 2. |
| 学科分类 | 09 - 环境科学;08 - 地球科学 |
| 资助机构 | US-EPA |
| 项目经费 | 0 |
| 国家 | US |
| 语种 | 英语 |
| 文献类型 | 项目 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/77062 |
| 推荐引用方式 GB/T 7714 | John Veranth.Ultrafine Oil Aerosol Generation for Inhalation Studies.1999. |
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