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MODELING AND FORECASTING THE IMPACT OF THE LOWER ATMOSPHERE ON THE THERMOSPHERE IONOSPHERE SYSTEM
项目编号NNX11AO61G
TIM FULLER-ROWELL
项目主持机构UNIVERSITY OF COLORADO, BOULDER
开始日期2011-08-02
结束日期2014-08-01
英文摘要There is a growing awareness that exposure to environmental contaminants such as fine particulate matter and diesel particulates can trigger or exacerbate diseases such as asthma and cardiovascular disease, but there is still much uncertainty about the importance of specific factors and the relationship between disease and exposure. Asthma affects between 14 and 15 million people in the United States, about 4.8 million of whom are children; its incidence worldwide has doubled in the last 15 years; and it is responsible for 100 million person-days of restricted activity and 5000 deaths per year, amounting to $8.1 billion in direct health related costs. Endotoxin, a ubiquitous component of gram-negative bacteria, is an important bioactive environmental factor that can induce asthma symptoms: bronchoconstriction, airways inflammation and airways hyper-responsiveness. Endotoxin levels, which are known to be highly variable in space and time, have been correlated with asthma symptoms and disease severity. The proposed project will develop an improved personal exposure monitor that can be used to obtain space- and time-resolved measurements of endotoxin contained in airborne particles in a portable device that can be used in studies to develop a better understanding of the relationships between exposure and human health impacts.
英文关键词10 year old;aerosolized;Aerosols;Affect;Agitation;airway hyperresponsiveness;airway inflammation;Aliquot;Asthma;Automation;Awareness;Back;Biological Assay;Bronchoconstriction;Cardiovascular Diseases;Cells;Cessation of life;Child;Cohort Studies;Collaborations;Collection;cost;design;Detection;Development;Devices;Disease;Elements;Endotoxins;Environment;Environmental Exposure;Environmental Pollution;Environmental Risk Factor;Epidemiologic Studies;Escherichia coli;Event;Excision;exposed human population;Exposure to;Genetic;Gram-Negative Bacteria;Health;Hour;Human;improved;Incidence;Individual;Injection of therapeutic agent;Laboratories;light (weight);Liquid substance;Location;Measurement;Microfluidics;miniaturize;Molds;Monitor;Motion;novel;operation;Pacific Northwest;particle;Particulate;Particulate Matter;Performance;Persons;Phase;Population;Positioning Attribute;Procedures;prototype;Recording of previous events;Research;Research Personnel;Sampling;Science;Series;Severity of illness;Suggestion;Symptoms;System;Systems Integration;Technology;Testing;Time;tool;Travel;Ultrasonics;Uncertainty;United States;Universities;usability;Washington;Work;Workload
学科分类11 - 工程与技术;1107 - 航空航天工程;03 - 天文学
资助机构US-NASA
国家US
语种英语
文献类型项目
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/75585
推荐引用方式
GB/T 7714
TIM FULLER-ROWELL.MODELING AND FORECASTING THE IMPACT OF THE LOWER ATMOSPHERE ON THE THERMOSPHERE IONOSPHERE SYSTEM.2011.
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