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| Genetic epigenetic & transcripotomic effects of e-cig aerosol on oral epithelium | |
| 项目编号 | 1R01DE026043-01 |
| BESARATINIA, AHMAD | |
| 项目主持机构 | UNIVERSITY OF SOUTHERN CALIFORNIA |
| 开始日期 | 2016-03-03 |
| 结束日期 | 2020-2-29 |
| 英文摘要 | PUBLIC HEALTH RELEVANCE: Exposure to complex environmental agents, such as ultrafine particulate matter derived from diesel exhaust and engineered nanomaterial is complex and not well understood, it can lead to toxicological responses or cardiovascular disease. The toxic potential of inhaled particles is dependent on the particle size and chemical composition. This research addresses the need for a better method of personal exposure assessment, which can quantify and characterize ultrafine particles in the environment. |
| 英文关键词 | Address;Aerosols;Affect;Area;Artificial nanoparticles;Asthma;Awareness;base;Biochemical Reaction;Biological Assay;Breathing;Cardiovascular Diseases;cardiovascular health;Cells;Cessation of life;Charge;Chemicals;Chemistry;Child;Chronic Obstructive Airway Disease;Collection;Commuting;Complex;consumer product;cost;cost effective;Couples;Data;Data Storage and Retrieval;Deposition;design;Detection;Diesel Exhaust;Dithiothreitol;Dyes;Electrostatics;Engineering;Environment;environmental agent;Environmental Exposure;Environmental Impact;Environmental Monitoring;Equipment;Exposure to;Feedback;field study;flexibility;Gold;Guanine Nucleotide Dissociation Inhibitors;Health;Household;Image;improved;In Situ;Incidence;Individual;Industry;instrument;Laboratories;Laboratory Study;Lead;Marketing;Measurement;Metals;Methods;Microfluidic Analytical Techniques;Microfluidic Microchips;Microfluidics;Military Personnel;miniaturize;Monitor;monitoring device;nanomaterials;nanoparticle;novel;Occupational;operation;Outcome;particle;Particle Size;Particulate;Particulate Matter;Performance;Persons;Pharmacologic Substance;Phase;phase 1 study;population health;Positioning Attribute;prototype;public health relevance;rapid growth;Reactive Oxygen Species;Reducing Agents;Reference Standards;Research;Research Personnel;research study;residence;Respiratory System;Respiratory tract structure;response;Sampling;Security;Semiconductors;Silver;Solubility;surveillance network;Techniques;Technology;Testing;Time;Tissues;tool;trafficking;Ultrafine;ultrafine particle;Uncertainty;United States;uptake;usability |
| 资助机构 | US-NIH |
| 项目经费 | 401125 |
| 项目类型 | Non-SBIR/STTR RPGs |
| 国家 | US |
| 语种 | 英语 |
| 文献类型 | 项目 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/73683 |
| 推荐引用方式 GB/T 7714 | BESARATINIA, AHMAD.Genetic epigenetic & transcripotomic effects of e-cig aerosol on oral epithelium.2016. |
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