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| Vergleich der zellulären Antwort zwischen humanem respiratorischen Primärgewebe und 3D-Co-Kulturen auf Bariumsulfat-Nanopartikel-Aerosol | |
| 项目编号 | http://gepris.dfg.de/gepris/projekt/397981139 |
| sProfessorin Dr. HeidiFoth | |
| 项目主持机构 | Martin-Luther-Universität Halle-Wittenberg |
| 开始日期 | 2018 |
| 英文摘要 | Thisprojectincludesfurtherfundamentalinvestigationsontheprocessofaerosoldepositionofceramicpowders,alsoknownasaerosoldepositionmethod(ADM),thatarebasedonmorerecentfindingsofthedepositionmechanism.Forexample,reducedfunctionalpropertiescomparedtobulkmaterial(especiallywithregardtoionicorelectronicconductivity)canbeobservedforallcoatingsproducedbyADMdirectlyafterdeposition.Bymeansofathermalpost-treatmentaftertheADprocess,thesepropertiescanbepermanentlyrestoredsothatthepropertiesofthefilmsreachpermanentlythepropertiesofthebulkmaterial.Thetemperaturesrequiredforthisimprovementaresignificantlybelowthetemperaturerequiredforgraingrowth.ThereasonforthepoorerfunctionalpropertiesofADcoatingsdirectlyaftercoatingistheprocess-relatedgenerationofmechanicalmicro-stressesduringlayerformation.Thisisthepointatwhichthepresentapplicationcomesintoplay.ThefocushereisonreducingorcompletelyavoidingthermaltreatmentthatfollowstheADprocess.Thisistobemadepossiblebyaddingchemicallyandelectricallyinertfillers(CaF2,PE/PPandAl2O3)tothefunctionalmaterials(YSZ,STF).Thefillermaterialhasthefunctionofamechanicalbuffermaterial,wherebyareductionofthelayer-immanentmicro-stressesisachieved.Theexactinfluenceofthefillermaterialonthecoatingprocessiscurrentlyunclear.Inordertoqualitativelyandquantitativelyassessthecorrelationbetweentheinertfillerandthefunctionalmaterialonthepropertiesofthelayer,severalfillingmaterialsandtwofunctionalmaterialsarecombinedwitheachother.ADMiscarriedoutasaco-depositionofpowdermixtures.Inaddition,themixingratiosofthecorrespondingpowdermixturesarevaried.Withincreasingadditionoffillermaterial,itisassumedthatontheonehandfilm-immanenttensionscanbereduced.Ontheotherhand,however,dilutionoccursandthefunctionalpropertiesofthecoating,whicharebasedonthefunctionalmaterial,arereduced.Inordertoachievethehighestpossibleproportionoffunctionalmaterialinthemixture,theconstructionofagradientlayerisanintegralpartofthelastpartoftheproject.Dependingonthethicknessofthecoating,theproportionoffunctionalmaterialinthemixtureistobevariedinordertocreatethicklayerswithminimalstressesandahighproportionoffunctionalmaterial.Theinvestigationsinthecourseoftheprojectareintendedtobroadenthefundamentalunderstandingofthelayerformationprocess,wherebyinfuturenew,especiallylowmeltingpointcomponentscombinedwithgoodfunctionalpropertiescanbebondedbymeansofaerosoldepositionatroomtemperature. |
| 学科分类 | 14 - 医学科学 |
| 资助机构 | DE-DFG |
| 项目类型 | Research Grants |
| 国家 | DE |
| 语种 | 英语 |
| 文献类型 | 项目 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/73289 |
| 推荐引用方式 GB/T 7714 | sProfessorin Dr. HeidiFoth.Vergleich der zellulären Antwort zwischen humanem respiratorischen Primärgewebe und 3D-Co-Kulturen auf Bariumsulfat-Nanopartikel-Aerosol.2018. |
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