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DOI | 10.1016/j.bbagen.2016.05.035 |
A paler shade of green? The toxicology of biodiesel emissions: Recent findings from studies with this alternative fuel | |
Madden, Michael C. | |
发表日期 | 2016-12-01 |
ISSN | 0304-4165 |
卷号 | 1860期号:12页码:2856-2862 |
英文摘要 | Background: Biodiesel produced primarily from plants and algal feedstocks is believed to have advantages for production and use compared to petroleum and to some other fuel sources. There is some speculation that exposure to biodiesel combustion emissions may not induce biological responses or health effects or at a minimum reduce the effects relative to other fuels. In evaluating the overall environmental and health effects of biodiesel production to end use scenario, empirical data or modeling data based on such data are needed. Scope of review: This manuscript examines the available toxicology reports examining combustion derived bio-diesel emissions since approximately 2007, when our last review of the topic occurred. Toxicity derived from other end uses of biodiesel - e.g., spills, dermal absorption, etc. - are not examined. Findings from biodiesel emissions are roughly divided into three areas: whole non-human animal model exposures; in vitro exposures of mammalian and bacterial cells (used for mutation studies primarily); and human exposures in controlled or other exposure fashions. Major conclusions: Overall, these more current studies clearly demonstrate that biodiesel combustion emission exposure- to either 100% biodiesel or a blend in petroleum diesel- can induce biological effects. There are reports that show biodiesel exposure generally induces more effects or a greater magnitude of effect than petroleum diesel, however there are also a similar number of reports showing the opposite trend. It is unclear whether effects induced by exposure to a blend are greater than exposure to 100% biodiesel. Taken together, the evidence suggest biodiesel emissions can have some similar effects as diesel emissions on inflammatory, vascular, mutagenic, and other responses. General significance: While acute biodiesel exposures can show toxicity with a variety of endpoints, the potential effects on human health need further validation. Additionally there are few or no findings to date on whether bio-diesel emissions can induce effects or even a weaker response that petroleum diesel with repeated exposure scenarios such as in an occupational setting. (C) 2016 Published by Elsevier B.V. |
英文关键词 | Biodiesel emissions;Petroleum diesel;Lung toxicity;Cardiovascular toxicity;Mutagenicity |
语种 | 英语 |
WOS记录号 | WOS:000384866700010 |
来源期刊 | BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS |
来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/62346 |
作者单位 | US EPA, Natl Hlth & Environm Effects Res Lab, Off Res & Dev, Chapel Hill, NC 27514 USA |
推荐引用方式 GB/T 7714 | Madden, Michael C.. A paler shade of green? The toxicology of biodiesel emissions: Recent findings from studies with this alternative fuel[J]. 美国环保署,2016,1860(12):2856-2862. |
APA | Madden, Michael C..(2016).A paler shade of green? The toxicology of biodiesel emissions: Recent findings from studies with this alternative fuel.BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS,1860(12),2856-2862. |
MLA | Madden, Michael C.."A paler shade of green? The toxicology of biodiesel emissions: Recent findings from studies with this alternative fuel".BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1860.12(2016):2856-2862. |
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