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Evidence-based Toxicology for the 21st Century: Opportunities and Challenges | |
Stephens, Martin L.1; Andersen, Melvin2; Becker, Richard A.3; Betts, Kellyn; Boekelheide, Kim4; Carney, Ed5; Chapin, Robert6; Devlin, Dennis7; Fitzpatrick, Suzanne8; Fowle, John R., III9; Harlow, Patricia10; Hartung, Thomas1; Hoffmann, Sebastian11; Holsapple, Michael12; Jacobs, Abigail10; Judson, Richard13; Naidenko, Olga14; Pastoor, Tim15; Patlewicz, Grace16; Rowan, Andrew17; Scherer, Roberta1; Shaikh, Rashid18; Simon, Ted19; Wolf, Douglas13; Zurlo, Joanne1 | |
发表日期 | 2013 |
ISSN | 1868-596X |
卷号 | 30期号:1页码:74-103 |
英文摘要 | The Evidence-based Toxicology Collaboration (EBTC) was established recently to translate evidence-based approaches from medicine and health care to toxicology in an organized and sustained effort. The EBTC held a workshop on "Evidence-based Toxicology for the 21st Century: Opportunities and Challenges" in Research Triangle Park, North Carolina, USA on January 24-25, 2012. The presentations largely reflected two EBTC priorities: to apply evidence-based methods to assessing the performance of emerging pathway-based testing methods consistent with the 2007 National Research Council report on "Toxicity Testing in the 21st Century" as well as to adopt a governance structure and work processes to move that effort forward. The workshop served to clarify evidence-based approaches and to provide food for thought on substantive and administrative activities for the EBTC. Priority activities include conducting pilot studies to demonstrate the value of evidence-based approaches to toxicology, as well as conducting educational outreach on these approaches. |
英文关键词 | evidence-based toxicology;evidence-based medicine;systematic review;validation;test method assessment |
语种 | 英语 |
WOS记录号 | WOS:000315012800007 |
来源期刊 | ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
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来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/61952 |
作者单位 | 1.Johns Hopkins Univ, Baltimore, MD USA; 2.Hamner Inst Hlth Sci, Res Triangle Pk, NC USA; 3.Amer Chem Council, Washington, DC USA; 4.Brown Univ, Providence, RI 02912 USA; 5.Dow Chem, Midland, MI USA; 6.Pfizer Global R&D, Groton, CT USA; 7.ExxonMobil, Irving, TX USA; 8.US FDA, College Pk, MD USA; 9.US EPA, Pittsboro, NC USA; 10.US FDA, Silver Spring, MD USA; 11.Seh Consulting Serv, Paderborn, Germany; 12.Battelle Mem Inst, Columbus, OH USA; 13.US EPA, Res Triangle Pk, NC 27711 USA; 14.Environm Working Grp, Washington, DC USA; 15.Syngenta, Greensboro, NC USA; 16.DuPont Haskell Global Ctr Hlth & Environm Sci, Newark, DE USA; 17.Humane Soc Int, Gaithersburg, MD USA; 18.Hlth Effects Inst, Boston, MA USA; 19.Ted Simon LLC, Winston, GA USA |
推荐引用方式 GB/T 7714 | Stephens, Martin L.,Andersen, Melvin,Becker, Richard A.,et al. Evidence-based Toxicology for the 21st Century: Opportunities and Challenges[J]. 美国环保署,2013,30(1):74-103. |
APA | Stephens, Martin L..,Andersen, Melvin.,Becker, Richard A..,Betts, Kellyn.,Boekelheide, Kim.,...&Zurlo, Joanne.(2013).Evidence-based Toxicology for the 21st Century: Opportunities and Challenges.ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION,30(1),74-103. |
MLA | Stephens, Martin L.,et al."Evidence-based Toxicology for the 21st Century: Opportunities and Challenges".ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION 30.1(2013):74-103. |
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