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DOI10.1021/acs.est.5b03547
Estimating Potential Increased Bladder Cancer Risk Due to Increased Bromide Concentrations in Sources of Disinfected Drinking Waters
Regli, Stig1; Chen, Jimmy1; Messner, Michael1; Elovitz, Michael S.2; Letkiewicz, Frank J.3; Pegram, Rex A.4; Pepping, T. J.1,5; Richardson, Susan D.6; Wright, J. Michael7
发表日期2015-11-17
ISSN0013-936X
卷号49期号:22页码:13094-13102
英文摘要

Public water systems are increasingly facing higher bromide levels in their source waters from anthropogenic contamination through coal-fired power plants, conventional oil and gas extraction, textile mills, and hydraulic fracturing. Climate change is likely to exacerbate this in coming years. We estimate bladder cancer risk from potential increased bromide levels in source waters of disinfecting public drinking water systems in the United States. Bladder cancer is the health end point used by the United States Environmental Protection Agency (EPA) in its benefits analysis for regulating disinfection byproducts in drinking water. We use estimated increases in the mass of the four regulated trihalomethanes (THM4) concentrations (due to increased bromide incorporation) as the surrogate disinfection byproduct (DBP) occurrence metric for informing potential bladder cancer risk. We estimate potential increased excess lifetime bladder cancer risk as a function of increased source water bromide levels. Results based on data from 201 drinking water treatment plants indicate that a bromide increase of 50 mu g/L could result in a potential increase of between 10(-3) and 10(-4) excess lifetime bladder cancer risk in populations served by roughly 90% of these plants.


语种英语
WOS记录号WOS:000365151200002
来源期刊ENVIRONMENTAL SCIENCE & TECHNOLOGY
来源机构美国环保署
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/60494
作者单位1.US EPA, Off Ground Water & Drinking Water, Washington, DC 20460 USA;
2.US EPA, Off Res & Dev, Natl Risk Management Lab, Cincinnati, OH 45268 USA;
3.Cadmus Grp, Bethesda, MD 20814 USA;
4.US EPA, Off Res & Dev, Natl Hlth & Environm Effects Res Lab, Res Triangle Pk, NC 27711 USA;
5.US DOE, Oak Ridge Inst Sci & Educ Internship, Res Participat Program, Oak Ridge, TN 37830 USA;
6.Univ S Carolina, Dept Chem & Biochem, Columbia, SC 29208 USA;
7.US EPA, Off Res & Dev, Natl Ctr Environm Assessment, Cincinnati, OH 45268 USA
推荐引用方式
GB/T 7714
Regli, Stig,Chen, Jimmy,Messner, Michael,et al. Estimating Potential Increased Bladder Cancer Risk Due to Increased Bromide Concentrations in Sources of Disinfected Drinking Waters[J]. 美国环保署,2015,49(22):13094-13102.
APA Regli, Stig.,Chen, Jimmy.,Messner, Michael.,Elovitz, Michael S..,Letkiewicz, Frank J..,...&Wright, J. Michael.(2015).Estimating Potential Increased Bladder Cancer Risk Due to Increased Bromide Concentrations in Sources of Disinfected Drinking Waters.ENVIRONMENTAL SCIENCE & TECHNOLOGY,49(22),13094-13102.
MLA Regli, Stig,et al."Estimating Potential Increased Bladder Cancer Risk Due to Increased Bromide Concentrations in Sources of Disinfected Drinking Waters".ENVIRONMENTAL SCIENCE & TECHNOLOGY 49.22(2015):13094-13102.
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