Climate Change Data Portal
DOI | 10.1136/oemed-2014-102468 |
A systematic review of the association between pleural plaques and changes in lung function | |
Kopylev, Leonid; Christensen, Krista Yorita; Brown, James S.; Cooper, Glinda S. | |
发表日期 | 2015-08-01 |
ISSN | 1351-0711 |
卷号 | 72期号:8页码:606-614 |
英文摘要 | Objectives To conduct a systematic review of changes in lung function in relation to presence of pleural plaques in asbestos-exposed populations. Methods Database searches of PubMed and Web of Science were supplemented by review of papers' reference lists and journals' tables of contents. Methodological features (eg, consideration of potential confounding by smoking) of identified articles were reviewed by >= two reviewers. Meta-analyses of 20 studies estimated a summary effect of the decrements in per cent predicted (% pred) forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) associated with presence of pleural plaques. Results Among asbestos-exposed workers, the presence of pleural plaques was associated with statistically significant decrements in FVC (4.09% pred, 95% CI 2.31 to 5.86) and FEV1 (1.99%pred, 95% CI 0.22 to 3.77). Effects of similar magnitude were seen when stratifying by imaging type (X-ray or high-resolution CT) and when excluding studies with potential methodological limitations. Undetected asbestosis was considered as an unlikely explanation of the observed decrements. Several studies provided evidence of an association between size of pleural plaques and degree of pulmonary decrease, and presence of pleural plaques and increased rate or degree of pulmonary impairment. Conclusions The presence of pleural plaques is associated with a small, but statistically significant mean difference in FVC and FEV1 in comparison to asbestos-exposed individuals without plaques or other abnormalities. From a public health perspective, small group mean decrements in lung function coupled with an increased rate of decline in lung function of the exposed population may be consequential. |
语种 | 英语 |
WOS记录号 | WOS:000358020600012 |
来源期刊 | OCCUPATIONAL AND ENVIRONMENTAL MEDICINE |
来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/58658 |
作者单位 | US EPA, Natl Ctr Environm Assessment, Off Res & Dev, Washington, DC 20460 USA |
推荐引用方式 GB/T 7714 | Kopylev, Leonid,Christensen, Krista Yorita,Brown, James S.,et al. A systematic review of the association between pleural plaques and changes in lung function[J]. 美国环保署,2015,72(8):606-614. |
APA | Kopylev, Leonid,Christensen, Krista Yorita,Brown, James S.,&Cooper, Glinda S..(2015).A systematic review of the association between pleural plaques and changes in lung function.OCCUPATIONAL AND ENVIRONMENTAL MEDICINE,72(8),606-614. |
MLA | Kopylev, Leonid,et al."A systematic review of the association between pleural plaques and changes in lung function".OCCUPATIONAL AND ENVIRONMENTAL MEDICINE 72.8(2015):606-614. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。