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DOI10.1038/jes.2017.29
Consumer product chemical weight fractions from ingredient lists
Isaacs, Kristin K.1; Phillips, Katherine A.1; Biryol, Derya1,2; Dionisio, Kathie L.1; Price, Paul S.1
发表日期2018-05-01
ISSN1559-0631
卷号28期号:3页码:216-222
英文摘要

Assessing human exposures to chemicals in consumer products requires composition information. However, comprehensive composition data for products in commerce are not generally available. Many consumer products have reported ingredient lists that are constructed using specific guidelines. A probabilistic model was developed to estimate quantitative weight fraction (WF) values that are consistent with the rank of an ingredient in the list, the number of reported ingredients, and labeling rules. The model provides the mean, median, and 95% upper and lower confidence limit WFs for ingredients of any rank in lists of any length. WFs predicted by the model compared favorably with those reported on Material Safety Data Sheets. Predictions for chemicals known to provide specific functions in products were also found to reasonably agree with reported WFs. The model was applied to a selection of publicly available ingredient lists, thereby estimating WFs for 1293 unique ingredients in 1123 products in 81 product categories. Predicted WFs, although less precise than reported values, can be estimated for large numbers of product-chemical combinations and thus provide a useful source of data for high-throughput or screening-level exposure assessments.


英文关键词consumer products;consumer exposures;ExpoCast;ingredients
语种英语
WOS记录号WOS:000430457100002
来源期刊JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
来源机构美国环保署
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/58590
作者单位1.US EPA, Off Res & Dev, Natl Exposure Res Lab, E205-02,109 TW Alexander Dr, Res Triangle Pk, NC 27709 USA;
2.Oak Ridge Inst Sci & Educ, Oak Ridge, TN 37830 USA
推荐引用方式
GB/T 7714
Isaacs, Kristin K.,Phillips, Katherine A.,Biryol, Derya,et al. Consumer product chemical weight fractions from ingredient lists[J]. 美国环保署,2018,28(3):216-222.
APA Isaacs, Kristin K.,Phillips, Katherine A.,Biryol, Derya,Dionisio, Kathie L.,&Price, Paul S..(2018).Consumer product chemical weight fractions from ingredient lists.JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY,28(3),216-222.
MLA Isaacs, Kristin K.,et al."Consumer product chemical weight fractions from ingredient lists".JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY 28.3(2018):216-222.
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