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DOI | 10.1016/j.acra.2017.05.007 |
The Reproducibility of Changes in Diagnostic Figures of Merit Across Laboratory and Clinical Imaging Reader Studies | |
Samuelson, Frank W.1; Abbey, Craig K.2 | |
发表日期 | 2017-11-01 |
ISSN | 1076-6332 |
卷号 | 24期号:11页码:1436-1446 |
英文摘要 | Rationale and Objectives: In this paper we examine which comparisons of reading performance between diagnostic imaging systems made in controlled retrospective laboratory studies may be representative of what we observe in later clinical studies. The change in a meaningful diagnostic figure of merit between two diagnostic modalities should be qualitatively or quantitatively comparable across all kinds of studies. Materials and Methods: In this meta-study we examine the reproducibility of relative measures of sensitivity, false positive fraction (FPF), area under the receiver operating characteristic (ROC) curve, and expected utility across laboratory and observational clinical studies for several different breast imaging modalities, including screen film mammography, digital mammography, breast tomosynthesis, and ultrasound. Results: Across studies of all types, the changes in the FPFs yielded very small probabilities of having a common mean value. The probabilities of relative sensitivity being the same across ultrasound and tomosynthesis studies were low. No evidence was found for different mean values of relative area under the ROC curve or relative expected utility within any of the study sets. Conclusion: The comparison demonstrates that the ratios of areas under the ROC curve and expected utilities are reproducible across laboratory and clinical studies, whereas sensitivity and FPF are not. |
英文关键词 | Sensitivity;specificity;AUC;reproducibility |
语种 | 英语 |
WOS记录号 | WOS:000413992500014 |
来源期刊 | ACADEMIC RADIOLOGY |
来源机构 | 美国环保署 |
文献类型 | 期刊论文 |
条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/58032 |
作者单位 | 1.US EPA, 10903 New Hampshire Ave,Bldg 62,Room 3102, Silver Spring, MD 20993 USA; 2.Univ Calif Santa Barbara, Dept Psychol & Brain Sci, Santa Barbara, CA 93106 USA |
推荐引用方式 GB/T 7714 | Samuelson, Frank W.,Abbey, Craig K.. The Reproducibility of Changes in Diagnostic Figures of Merit Across Laboratory and Clinical Imaging Reader Studies[J]. 美国环保署,2017,24(11):1436-1446. |
APA | Samuelson, Frank W.,&Abbey, Craig K..(2017).The Reproducibility of Changes in Diagnostic Figures of Merit Across Laboratory and Clinical Imaging Reader Studies.ACADEMIC RADIOLOGY,24(11),1436-1446. |
MLA | Samuelson, Frank W.,et al."The Reproducibility of Changes in Diagnostic Figures of Merit Across Laboratory and Clinical Imaging Reader Studies".ACADEMIC RADIOLOGY 24.11(2017):1436-1446. |
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