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DOI10.1080/10807039.2013.764771
Exploratory Cumulative Risk Assessment (CRA) Approaches Using Secondary Data
Evans, Amanda M.1,2; Rice, Glenn E.2; Wright, J. Michael2; Teuschler, Linda K.2
发表日期2014-05-04
ISSN1080-7039
卷号20期号:3页码:704-723
英文摘要

Cumulative risk assessments (CRAs) include the examination of risks posed by multiple stressors and include population-specific vulnerabilities and susceptibilities. In this case study, we assess potential hearing impairment hazard due to joint exposure from noise and volatile organic compounds (VOCs) in order to examine the strengths and limitations of using secondary data on exposure and health effects for a CRA. Block group-level noise categories were estimated using modeled street-level data. A quantile regression model of sociodemographic and personal predictors from the 1999-2000U.S. National Health and Nutrition Examination Survey VOC dataset was used along with block group-level sociodemographic and personal variables to estimate VOC exposures. Hazard indices (HIs) for potential hearing impairment due to joint noise and VOC exposures were calculated. County-averaged HIs for hearing impairment ranged from 0.8 (10th total VOCs percentile and 45-60dB) to 1.7 (90th total VOCs percentile and 71-75dB). Limitations of the exposure and health effects data included issues combining heterogeneous data and a lack of established threshold levels for combined low-level exposures; yet, this case study illustrates that screening-level CRAs, including non-chemical stressors, can be accomplished with publicly available data and existing methods.


英文关键词cumulative risk assessment;joint exposures;secondary data analysis;hazard index;non-chemical stressors;chemical mixtures
语种英语
WOS记录号WOS:000330020700009
来源期刊HUMAN AND ECOLOGICAL RISK ASSESSMENT
来源机构美国环保署
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/56839
作者单位1.Assoc Sch Publ Hlth, Washington, DC USA;
2.US EPA, Natl Ctr Environm Assessment, Off Res & Dev, Cincinnati, OH 45268 USA
推荐引用方式
GB/T 7714
Evans, Amanda M.,Rice, Glenn E.,Wright, J. Michael,et al. Exploratory Cumulative Risk Assessment (CRA) Approaches Using Secondary Data[J]. 美国环保署,2014,20(3):704-723.
APA Evans, Amanda M.,Rice, Glenn E.,Wright, J. Michael,&Teuschler, Linda K..(2014).Exploratory Cumulative Risk Assessment (CRA) Approaches Using Secondary Data.HUMAN AND ECOLOGICAL RISK ASSESSMENT,20(3),704-723.
MLA Evans, Amanda M.,et al."Exploratory Cumulative Risk Assessment (CRA) Approaches Using Secondary Data".HUMAN AND ECOLOGICAL RISK ASSESSMENT 20.3(2014):704-723.
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