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DOI10.1289/EHP644
Scientific Challenges in the Risk Assessment of Food Contact Materials
Muncke, Jane1; Backhaus, Thomas2; Geueke, Birgit1; Maffini, Maricel V.; Martin, Olwenn Viviane3; Myers, John Peterson4,5; Soto, Ana M.6; Trasande, Leonardo7; Trier, Xenia8,9; Scheringer, Martin10,11
发表日期2017
ISSN0091-6765
卷号125期号:9
英文关键词

BACKGROUND: Food contact articles (FCAs) are manufactured from food contact materials (FCMs) that include plastics, paper, metal, glass, and printing inks. Chemicals can migrate from FCAs into food during storage, processing, and transportation. Food contact materials' safety is evaluated using chemical risk assessment (RA). Several challenges to the RA of FCAs exist.


OBJECTIVES: We review regulatory requirements for RA of FCMs in the United States and Europe, identify gaps in RA, and highlight opportunities for improving the protection of public health. We intend to initiate a discussion in the wider scientific community to enhance the safety of food contact articles.


DISCUSSION: Based on our evaluation of the evidence, we conclude that current regulations are insufficient for addressing chemical exposures from FCAs. RA currently focuses on monomers and additives used in the manufacture of products, but it does not cover all substances formed in the production processes. Several factors hamper effective RA for many FCMs, including a lack of information on chemical identity, inadequate assessment of hazardous properties, and missing exposure data. Companies make decisions about the safety of some food contact chemicals (FCCS) without review by public authorities. Some chemical migration limits cannot he enforced because analytical standards arc unavailable.


CONCLUSION: We think that exposures to hazardous substances migrating from FCAs require more attention. We recommend a) limiting the number and types of chemicals authorized for manufacture and b) developing novel approaches for assessing the safety of chemicals in FCAs, including unidentified chemicals that form during or after production.


语种英语
WOS记录号WOS:000413792800008
来源期刊ENVIRONMENTAL HEALTH PERSPECTIVES
来源机构欧洲环境署
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/56304
作者单位1.Food Packaging Forum Fdn, Zurich, Switzerland;
2.Univ Gothenburg, Dept Biol & Environm Sci, Gothenburg, Sweden;
3.Brunel Univ London, Inst Environm, Uxbridge, Middx, England;
4.Environm Hlth Sci, Charlottesville, VA USA;
5.Carnegie Mellon Univ, Dept Chem, Pittsburgh, PA USA;
6.Tufts Univ, Sch Med, Dept Integrat Physiol & Pathobiol, Boston, MA 02111 USA;
7.NYU, Sch Med, Dept Pediat, New York, NY USA;
8.Tech Univ Denmark, DTU Food, Copenhagen, Denmark;
9.European Environm Agcy, Copenhagen, Denmark;
10.Masaryk Univ, Res Ctr Tox Cpds Environm, Brno, Czech Republic;
11.Swiss Fed Inst Technol, Inst Chem & Bioengn, Zurich, Switzerland
推荐引用方式
GB/T 7714
Muncke, Jane,Backhaus, Thomas,Geueke, Birgit,et al. Scientific Challenges in the Risk Assessment of Food Contact Materials[J]. 欧洲环境署,2017,125(9).
APA Muncke, Jane.,Backhaus, Thomas.,Geueke, Birgit.,Maffini, Maricel V..,Martin, Olwenn Viviane.,...&Scheringer, Martin.(2017).Scientific Challenges in the Risk Assessment of Food Contact Materials.ENVIRONMENTAL HEALTH PERSPECTIVES,125(9).
MLA Muncke, Jane,et al."Scientific Challenges in the Risk Assessment of Food Contact Materials".ENVIRONMENTAL HEALTH PERSPECTIVES 125.9(2017).
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