气候变化领域集成服务门户(CCPortal): Effects of heat waves and cold spells on blood parameters: a cohort study of blood donors in Tianjin, China

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DOI	10.1265/ehpm.24-00023
	Effects of heat waves and cold spells on blood parameters: a cohort study of blood donors in Tianjin, China
	Gao, Yutong; Liu, Yifan; He, Jiayu; Zhang, Yin; Wang, Ting; Wu, Lin; Sun, Naixiu; Fang, Tiange; Mao, Hongjun; Tang, Nai-jun; Chen, Xi
发表日期	2024
ISSN	1342-078X
EISSN	1347-4715
起始页码	29
卷号	29
英文摘要	Background: With the increasing occurrence of extreme temperature events due to climate change, the attention has been predominantly focused on the effects of heat waves and cold spells on morbidity and mortality. However, the influence of these temperature extremes on blood parameters has been overlooked. Methods: We conducted a cohort study involving 2,752 adult blood donors in Tianjin, China, between January 18, 2013, and June 25, 2021. The generalized additive mixed model was used to investigate the effects and lagged effects of heat waves and cold spells on six blood parameters of blood donors, including alanine aminotransferase (ALT), white blood cell count (WBC), red blood cell count (RBC), hemoglobin (HB), hematocrit (HCT), and platelet count (PLT). Subgroup analyses were stratified by sex, age, and BMI. Results: Heat waves and cold spells are associated with changes in blood parameters, particularly HB and PLT. Heat waves increased HB and PLT, while cold spells increased HB and decreased PLT. The effect of heat waves is greater than that of cold spells. The largest effect of heat waves on HB and PLT occurred at lag1 with 2.6 g/L (95% CI: 1.76 to 3.45) and lag7 with 9.71 (c) 10<^>9/L (95% CI: 6.26 to 13.17), respectively, while the largest effect of cold spells on HB and PLT occurred at lag0 with 1.02 g/L (95% CI: 0.71 to 1.33) and lag2 with -3.85 (c) 10<^>9/L (95% CI: -5.00 to -2.70), respectively. In subgroup analysis, the effect of cold spells on ALT was greater in the 40-49 age group. Conclusion: We indicated that heat waves and cold spells can impact hemoglobin and platelet counts in the human body. These findings provide evidence linking heat waves or cold spells to diseases and may reduce health risks caused by extreme temperature
英文关键词	Heat wave; Cold spell; Blood donors; Blood parameters; Generalized additive mixed model
语种	英语
WOS研究方向	Public, Environmental & Occupational Health
WOS类目	Public, Environmental & Occupational Health
WOS记录号	WOS:001222948600008
来源期刊	ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/304817
作者单位	Nankai University; Tianjin Medical University; Tianjin Medical University
推荐引用方式 GB/T 7714	Gao, Yutong,Liu, Yifan,He, Jiayu,et al. Effects of heat waves and cold spells on blood parameters: a cohort study of blood donors in Tianjin, China[J],2024,29.
APA	Gao, Yutong.,Liu, Yifan.,He, Jiayu.,Zhang, Yin.,Wang, Ting.,...&Chen, Xi.(2024).Effects of heat waves and cold spells on blood parameters: a cohort study of blood donors in Tianjin, China.ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE,29.
MLA	Gao, Yutong,et al."Effects of heat waves and cold spells on blood parameters: a cohort study of blood donors in Tianjin, China".ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE 29(2024).