气候变化领域集成服务门户(CCPortal): Ambient temperature anomalies induce electrocardiogram abnormalities: Findings from a nationwide longitudinal study

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DOI	10.1016/j.envres.2023.117996
	Ambient temperature anomalies induce electrocardiogram abnormalities: Findings from a nationwide longitudinal study
	Guo, Jian; Xue, Tao; Cao, Man; Han, Xueyan; Pan, Zhaoyang; Huang, Dengmin; Sun, Wei; Mi, Jiarun; Liu, Yuanli; Guan, Tianjia
发表日期	2024
ISSN	0013-9351
EISSN	1096-0953
起始页码	246
卷号	246
英文摘要	Electrocardiogram (ECG) outcomes serve as early manifestations of cardiovascular functional or structural changes. While temperature fluctuation has been demonstrated to be a risk factor for cardiovascular diseases, few epidemiological studies have reported its relationship with ECG outcomes. In this study, we employed temperature anomaly (TA) as an innovative indicator of temperature fluctuation to quantify its detrimental impacts on ECG outcomes. A longitudinal study design was conducted using the repeated ECG records of the China National Stroke Screening Survey from 2013 to 2019. Only individuals undergoing at least two ECG tests were included. The daily temperature was assimilated by combining three kinds of data: in situ observations, satellite remote sensing measurements and weather research forecast simulations. We used generalized estimating equations to control for autocorrelation among repeated records and to estimate the association between TA and the risk of ECG abnormalities. We found 6837 events of ECG abnormalities in 47,286 individuals with 102,030 visits. Each unit increment of TA increased the risk of ECG abnormalities [odds ratio (OR) = 1.009, 95% confidence interval (CI): 1.001-1.017] and the risk of myocardial ischemia (OR = 1.061, 95% CI: 1.012-1.111). Hierarchic analyses presented a similar association of TA with both ECG abnormalities (OR = 1.017, 95% CI: 1.008-1.026) and myocardial ischemia (OR = 1.061, 95%CI: 1.011-1.114) in Northern China, but not in Southern China. The exposure -response relationship was estimated as a U-shaped curve centered at the TA value of zero. Sudden warming tended to increase the risk of ECG abnormalities and myocardial ischemia, and sudden cooling tended to increase the risk of atrial fibrillation. All these detrimental effects of TA could be modified by specific individual characteristics. In summary, ambient temperature fluctuation increased the risk of ECG abnormalities. This result indicated that regular ECG tests could be an early -warning measure for monitoring the adverse health effects of temperature fluctuations.
英文关键词	Temperature anomaly; Climate change; Electrocardiogram; Longitudinal study; Association
语种	英语
WOS研究方向	Environmental Sciences & Ecology ; Public, Environmental & Occupational Health
WOS类目	Environmental Sciences ; Public, Environmental & Occupational Health
WOS记录号	WOS:001170294300001
来源期刊	ENVIRONMENTAL RESEARCH
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/304442
作者单位	Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College Hospital; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College Hospital; Peking University; Peking University; Peking University; Chinese Academy of Medical Sciences - Peking Union Medical College; Peking Union Medical College
推荐引用方式 GB/T 7714	Guo, Jian,Xue, Tao,Cao, Man,et al. Ambient temperature anomalies induce electrocardiogram abnormalities: Findings from a nationwide longitudinal study[J],2024,246.
APA	Guo, Jian.,Xue, Tao.,Cao, Man.,Han, Xueyan.,Pan, Zhaoyang.,...&Guan, Tianjia.(2024).Ambient temperature anomalies induce electrocardiogram abnormalities: Findings from a nationwide longitudinal study.ENVIRONMENTAL RESEARCH,246.
MLA	Guo, Jian,et al."Ambient temperature anomalies induce electrocardiogram abnormalities: Findings from a nationwide longitudinal study".ENVIRONMENTAL RESEARCH 246(2024).