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DOI	10.1002/ece3.11065
	Resource asynchrony and landscape homogenization as drivers of virulence evolution: The case of a directly transmitted disease in a social host
	Kuerschner, Tobias; Scherer, Cedric; Radchuk, Viktoriia; Blaum, Niels; Kramer-Schadt, Stephanie
发表日期	2024
ISSN	2045-7758
起始页码	14
结束页码	2
卷号	14 期号:2
英文摘要	Throughout the last decades, the emergence of zoonotic diseases and the frequency of disease outbreaks have increased substantially, fuelled by habitat encroachment and vectors overlapping with more hosts due to global change. The virulence of pathogens is one key trait for successful invasion. In order to understand how global change drivers such as habitat homogenization and climate change drive pathogen virulence evolution, we adapted an established individual-based model of host-pathogen dynamics. Our model simulates a population of social hosts affected by a directly transmitted evolving pathogen in a dynamic landscape. Pathogen virulence evolution results in multiple strains in the model that differ in their transmission capability and lethality. We represent the effects of global change by simulating environmental changes both in time (resource asynchrony) and space (homogenization). We found an increase in pathogenic virulence and a shift in strain dominance with increasing landscape homogenization. Our model further indicated that lower virulence is dominant in fragmented landscapes, although pulses of highly virulent strains emerged under resource asynchrony. While all landscape scenarios favoured co-occurrence of low- and high-virulent strains, the high-virulence strains capitalized on the possibility for transmission when host density increased and were likely to become dominant. With asynchrony likely to occur more often due to global change, our model showed that a subsequent evolution towards lower virulence could lead to some diseases becoming endemic in their host populations. During disease outbreaks, pathogenic virulence is a key trait for successful spread. Global change comes with an increasing frequency of novel zoonotic diseases or disease outbreaks. Here, we use an individual-based host-pathogen model to study how global change drivers affect virulence in a directly transmitted evolving pathogen in a social host. Our results show an increase in pathogenic virulence as an effect of increasing landscape homogenization.image
英文关键词	dynamic landscapes; evolution; global change; host-pathogen dynamics; virulence
语种	英语
WOS研究方向	Environmental Sciences & Ecology ; Evolutionary Biology
WOS类目	Ecology ; Evolutionary Biology
WOS记录号	WOS:001169987800001
来源期刊	ECOLOGY AND EVOLUTION
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/303765
作者单位	Leibniz Institut fur Zoo und Wildtierforschung; University of Potsdam; Technical University of Berlin
推荐引用方式 GB/T 7714	Kuerschner, Tobias,Scherer, Cedric,Radchuk, Viktoriia,et al. Resource asynchrony and landscape homogenization as drivers of virulence evolution: The case of a directly transmitted disease in a social host[J],2024,14(2).
APA	Kuerschner, Tobias,Scherer, Cedric,Radchuk, Viktoriia,Blaum, Niels,&Kramer-Schadt, Stephanie.(2024).Resource asynchrony and landscape homogenization as drivers of virulence evolution: The case of a directly transmitted disease in a social host.ECOLOGY AND EVOLUTION,14(2).
MLA	Kuerschner, Tobias,et al."Resource asynchrony and landscape homogenization as drivers of virulence evolution: The case of a directly transmitted disease in a social host".ECOLOGY AND EVOLUTION 14.2(2024).