气候变化领域集成服务门户(CCPortal): Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski's Gazelle

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DOI	10.3390/ani14071114
	Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski's Gazelle
	Ran, Yang; Li, Yuanfeng; Shen, Xiaoyun
发表日期	2024
ISSN	2076-2615
起始页码	14
结束页码	7
卷号	14 期号:7
英文摘要	Simple Summary: This study was designed to find the cause of microcytic anemia in the Przewalski's gazelle by investigating the mineral contents in its habitat. We found that the cause of the disease was selenium deficiency in the habitat, and then, a cure for the disease was discovered. It is extremely beneficial to protect the rare species of the Przewalski's gazelle. Due to the fencing of the Przewalski's gazelle (Procapra przewalskii), the microcytic anemia incidence rate continues to increase. The primary pathological symptoms include emaciation, anemia, pica, inappetence, and dyskinesia. To investigate the cause of microcytic anemia ailment in the Przewalski's gazelle, the Upper Buha River Area with an excessive incidence was chosen as the experimental pasture, and the Bird Island Area without microcytic anemia disease was chosen as the control field. Then, the mineral contents in the soil, forage, blood, and liver, as well as the blood routine parameters and biochemical indexes were measured. The findings showed that the experimental pasture had much lower Se content in the soil and forage than the control field (p < 0.01), while the impacted pasture had significantly higher S content in the forage. The damaged gazelles had considerably lower Se and Cu contents and higher S content in the blood and liver than the healthy gazelles (p < 0.01). The presences of Hb, HCT, MCV, and MCH were significantly decreased compared to those in healthy gazelles (p < 0.01). The experimental group had a significantly lower level of GSH-Px activity in their serums compared to the control group (p < 0.01). In the treatment experiment, ten gazelles from the affected pasture were orally administered CuSO4, 6 g/animal once every 10 days for two consecutive times, and all gazelles were successfully cured. Therefore, it is possible that low Se content in the soil induced an increase in the absorption of S content by forage, leading to the deficiency of secondary Cu in the Przewalski's gazelles, resulting in microcytic anemia.
英文关键词	Przewalski's gazelle; microcytic anemia; selenium nutrition; copper deprivation; the Qinghai-Tibet Plateau
语种	英语
WOS研究方向	Agriculture ; Veterinary Sciences ; Zoology
WOS类目	Agriculture, Dairy & Animal Science ; Veterinary Sciences ; Zoology
WOS记录号	WOS:001201558700001
来源期刊	ANIMALS
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/303634
作者单位	Southwest University of Science & Technology - China
推荐引用方式 GB/T 7714	Ran, Yang,Li, Yuanfeng,Shen, Xiaoyun. Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski's Gazelle[J],2024,14(7).
APA	Ran, Yang,Li, Yuanfeng,&Shen, Xiaoyun.(2024).Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski's Gazelle.ANIMALS,14(7).
MLA	Ran, Yang,et al."Studies of a Naturally Occurring Selenium-Induced Microcytic Anemia in the Przewalski's Gazelle".ANIMALS 14.7(2024).