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DOI	10.1016/j.scitotenv.2024.170148
	Unraveling the mystery of antibiotic resistance genes in green and red Antarctic snow
	Ren, Ze; Li, Huirong; Luo, Wei
发表日期	2024
ISSN	0048-9697
EISSN	1879-1026
起始页码	915
卷号	915
英文摘要	Antarctic snow is a thriving habitat for a diverse array of complex microorganisms, and can present in different colors due to algae blooms. However, the potential role of Antarctic snow as reservoirs for antibiotic resistance genes (ARGs) has not been studied. Using metagenomic sequencing, we studied ARGs in green-snow and redsnow on the Fildes Peninsula, Antarctica. Alpha and beta diversities of ARGs, as well as co-occurrence between ARGs and bacteria were assessed. The results showed that a total of 525 ARGs conferring resistance to 30 antibiotic classes were detected across the samples, with half of the ARGs presented in all samples. Green-snow exhibited a higher number of ARGs compared to red-snow. The most abundant ARGs conferring resistance to commonly used antibiotics, including disinfecting agents and antiseptics, peptide, isoniazid, MLS, fluoroquinolone, aminocoumarin, etc. Multidrug resistance genes stood out as the most diverse and abundant, with antibiotic efflux emerging as the dominant resistance mechanism. Interestingly, the composition of ARGs in green-snow markedly differed from that in red-snow, highlighting distinct ARG profiles. Beta-diversity partitioning showed a higher contribution of nestedness for ARG's variation in green-snow, while higher contribution of turnover in red-snow. Furthermore, the co-occurrence analysis between ARGs and bacteria unveiled intricate relationships, indicating that certain ARGs may have multiple potential hosts. The observed differences in cooccurrence networks between green-snow and red-snow suggested distinct host relationships between ARGs and bacteria in these colored snows. Given the increasing appearance of the colored snow around the world due to the climate change, the results shed light on the mystery and potential implication of ARGs in green and red Antarctic snow.
英文关键词	Antibiotic resistance genes; Colored-snow; Snow microbiome; beta-diversity; Fildes peninsula
语种	英语
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:001169642400001
来源期刊	SCIENCE OF THE TOTAL ENVIRONMENT
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/303027
作者单位	Chinese Academy of Sciences; Nanjing Institute of Geography & Limnology, CAS; Polar Research Institute of China; Ministry of Natural Resources of the People's Republic of China; Shanghai Jiao Tong University; Shanghai Jiao Tong University
推荐引用方式 GB/T 7714	Ren, Ze,Li, Huirong,Luo, Wei. Unraveling the mystery of antibiotic resistance genes in green and red Antarctic snow[J],2024,915.
APA	Ren, Ze,Li, Huirong,&Luo, Wei.(2024).Unraveling the mystery of antibiotic resistance genes in green and red Antarctic snow.SCIENCE OF THE TOTAL ENVIRONMENT,915.
MLA	Ren, Ze,et al."Unraveling the mystery of antibiotic resistance genes in green and red Antarctic snow".SCIENCE OF THE TOTAL ENVIRONMENT 915(2024).