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| DOI | 10.1002/prm2.12123 |
| A novel indicator for temperature control in heat stroke treatment | |
| 发表日期 | 2024 |
| ISSN | 2642-2514 |
| 起始页码 | 13 |
| 结束页码 | 1 |
| 卷号 | 13期号:1 |
| 英文摘要 | Background: Temperature control plays a pivotal role in patients with heat stroke (HS), but little work has been done sufficiently on the use of temperature control to reflect disease progression. Here, we defined and analyzed the concrete role of controlling time for core temperature to physiological level (CTTP), in order to explore a potential index to guide the treatment of HS.Method: This is a retrospective cohort study. From three hospitals located in Sichuan province, China, we collected a total of 179 HS cases with clinical diagnosis and treatment records. We defined CTTP as the time interval of HS onset to stabilization of core temperature (rectal temperature) below 37.7degree celsius and analyzed the correlation between CTTP and inpatient death of HS patients.Results: Of all the cases, 64.80% were male and 53.07% were exertional heat stroke (EHS). The median (IQR) age was 59 (23.5-73) years old, and the median (IQR) onset temperature was 42 (40.4-42)degree celsius. Multivariable analysis demonstrated significantly high inpatient death in the highest CTTP tertile (>18 h) (hazard ratio: 18.75; 99% confidence interval: 4.06-86.59; p = .0002). In addition, compared with patients in lowest CTTP tertile, patients in highest CTTP tertile were at significantly higher risk of organ damage: 3.48-fold for respiratory failure (95% CI: 1.41-8.59, p = .0069); 3.18-fold for shock (95% CI: 1.37-7.39, p = .0071); 4.09-fold for rhabdomyolysis (95% CI: 1.73-9.64, p = .0013); 4.64-fold for renal damage (95% CI: 2.12-10.14, p = .0001).Conclusion: Long of CTTP predicts inpatient death of HS patients with a CTTP tertile >18 h associated with the highest rate of inpatient death. |
| 英文关键词 | CTTP; heat stroke; inpatient death; organ damage |
| 语种 | 英语 |
| WOS研究方向 | Research & Experimental Medicine |
| WOS类目 | Medicine, Research & Experimental |
| WOS记录号 | WOS:001141632000001 |
| 来源期刊 | PRECISION MEDICAL SCIENCES
 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/301891 |
| 作者单位 | Chengdu University of Traditional Chinese Medicine |
| 推荐引用方式 GB/T 7714 | . A novel indicator for temperature control in heat stroke treatment[J],2024,13(1). |
| APA | (2024).A novel indicator for temperature control in heat stroke treatment.PRECISION MEDICAL SCIENCES,13(1). |
| MLA | "A novel indicator for temperature control in heat stroke treatment".PRECISION MEDICAL SCIENCES 13.1(2024). |
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