气候变化领域集成服务门户(CCPortal): Electrocardiogram Parameters Associated With the Diagnosis of Pulmonary Hypertension in High-Altitude Tibetan Populations: A Retrospective Single-Centre Study

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DOI	10.1016/j.hlc.2023.10.020
	Electrocardiogram Parameters Associated With the Diagnosis of Pulmonary Hypertension in High-Altitude Tibetan Populations: A Retrospective Single-Centre Study
	Dong, Ruimin; Liang, Yu 'en; Ni, Ma; Wang, Dengdi; Zhang, Juan; Dun, Zhu
发表日期	2024
ISSN	1443-9506
EISSN	1444-2892
起始页码	33
结束页码	2
卷号	33 期号:2
英文摘要	Background Electrocardiogram (ECG) is a commonly used diagnostic method for pulmonary hypertension (PH) in Tibetan areas, but its sensitivity and specificity are not good enough. This study aimed to investigate the ECG parameters associated with the diagnosis of PH in Tibetan areas. Methods Ninety-four PH patients of Tibetan ethnicity who were treated at the hospital between March 2019 and October 2020, and 52 Tibetan individuals as controls, were included. The ECG parameters were compared between groups. Multivariate logistic analysis was performed to identify the ECG parameters that can be used for the diagnosis of PH. The univariate significances of ECG parameters were included in the multivariate analyses, whereas those exhibiting opposite trends between different PH subtypes were excluded. Results Two ECG parameters were significant in multivariate analysis. The final model included S wave amplitude in lead V3 (OR 5.81; 95% CI 2.79-12.11; p<0.001) and a negative T wave in leads V1-V3 (OR 0.05; 95% CI 0.01-0.41; p=0.005). The ROC curve analysis on the final model yielded an AUC of 0.830 (95% CI 0.766-0.894; p<0.001), indicating good diagnostic performance. A nomogram for diagnosis of PH was also established using S wave amplitude in lead V3 and a negative T wave in leads V1-V3. Conclusion The ECG parameters S wave amplitude in lead V3 and a negative T wave in leads V1-V3 were independent factors associated with the diagnosis of PH in high -altitude Tibetan populations.
英文关键词	Pulmonary hypertension; Left heart disease; Electrocardiogram parameters; Diagnostic factors; Tibet
语种	英语
WOS研究方向	Cardiovascular System & Cardiology
WOS类目	Cardiac & Cardiovascular Systems
WOS记录号	WOS:001202299400001
来源期刊	HEART LUNG AND CIRCULATION
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/301701
作者单位	Sun Yat Sen University; Sun Yat Sen University
推荐引用方式 GB/T 7714	Dong, Ruimin,Liang, Yu 'en,Ni, Ma,et al. Electrocardiogram Parameters Associated With the Diagnosis of Pulmonary Hypertension in High-Altitude Tibetan Populations: A Retrospective Single-Centre Study[J],2024,33(2).
APA	Dong, Ruimin,Liang, Yu 'en,Ni, Ma,Wang, Dengdi,Zhang, Juan,&Dun, Zhu.(2024).Electrocardiogram Parameters Associated With the Diagnosis of Pulmonary Hypertension in High-Altitude Tibetan Populations: A Retrospective Single-Centre Study.HEART LUNG AND CIRCULATION,33(2).
MLA	Dong, Ruimin,et al."Electrocardiogram Parameters Associated With the Diagnosis of Pulmonary Hypertension in High-Altitude Tibetan Populations: A Retrospective Single-Centre Study".HEART LUNG AND CIRCULATION 33.2(2024).