气候变化领域集成服务门户(CCPortal): Antibiotic resistance genes profile in the surface sediments of typical aquaculture areas across 15 major lakes in China

CCPortal

DOI	10.1016/j.envpol.2024.123709
	Antibiotic resistance genes profile in the surface sediments of typical aquaculture areas across 15 major lakes in China
	Shi, Xiaomin; Shen, Zhangqi; Shao, Bing; Shen, Jianzhong; Wu, Yongning; Wang, Shaolin
发表日期	2024
ISSN	0269-7491
EISSN	1873-6424
起始页码	347
卷号	347
英文摘要	Aquatic farming is considered as a major source of antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs) for the natural environment of the lakes. ARB and ARGs in the natural environment have increased quickly because of the human activities. Here, we have profiled the diversity and abundance of ARGs in sediments from the typical aquaculture areas around 15 major lakes in China using PCR and qPCR, and further assessed the risk factor shaping the occurrence and distribution of ARGs. And class 1, 2 and 3 integrons were initially detected by PCR with specific primers. ARGs were widely distributed in the lakes: Weishan Lake and Poyang Lake showed high diversity of ARGs, followed by Dongting Lake, Chao Lake and Tai Lake. Generally, the ARGs in the Middle-Lower Yangtze Plain were more abundant than those in the Qinghai-Tibet Plateau. Tetracycline resistance genes (tet(C), tet(A) & tet(M)) were prominent in sediments, and the next was AmpC beta-lactamase gene group BIL/LAT/CMY, and the last was the genes resistance to aminoglycoside (strA-strB). Partial least squares path modeling analysis (PLS-PMA) revealed that livestock had a significant direct effect on the distribution of ARGs in lakes, and population might indirectly influence the profiles of ARGs by affecting the scale of livestock and aquaculture. The detectable rate of class 1, 2 and 3 integrons were 80%, 100% and 46.67%, respectively. The prevalence of integrons might play a key role in promoting more frequent horizontal gene transfer (HGT) events, resulting in the environmental mobilization and dissemination of ARGs between bacteria.
英文关键词	Sediments; Major lakes in China; ARGs; Socio-economic parameters
语种	英语
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:001202462300001
来源期刊	ENVIRONMENTAL POLLUTION
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/299064
作者单位	China Agricultural University; Beijing University of Agriculture; Chinese Academy of Medical Sciences - Peking Union Medical College
推荐引用方式 GB/T 7714	Shi, Xiaomin,Shen, Zhangqi,Shao, Bing,et al. Antibiotic resistance genes profile in the surface sediments of typical aquaculture areas across 15 major lakes in China[J],2024,347.
APA	Shi, Xiaomin,Shen, Zhangqi,Shao, Bing,Shen, Jianzhong,Wu, Yongning,&Wang, Shaolin.(2024).Antibiotic resistance genes profile in the surface sediments of typical aquaculture areas across 15 major lakes in China.ENVIRONMENTAL POLLUTION,347.
MLA	Shi, Xiaomin,et al."Antibiotic resistance genes profile in the surface sediments of typical aquaculture areas across 15 major lakes in China".ENVIRONMENTAL POLLUTION 347(2024).