气候变化领域集成服务门户(CCPortal): The branched mitochondrial respiratory chain from the jellyfish Stomolophus sp2 as a probable adaptive response to environmental changes

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DOI	10.1007/s10863-023-09999-y
	The branched mitochondrial respiratory chain from the jellyfish Stomolophus sp2 as a probable adaptive response to environmental changes
	Nevarez-Lopez, C. A.; Muhlia-Almazan, A.; Gamero-Mora, E.; Sanchez-Paz, A.; Sastre-Velasquez, C. D.; Lopez-Martinez, J.
发表日期	2024
ISSN	0145-479X
EISSN	1573-6881
起始页码	56
结束页码	2
卷号	56 期号:2
英文摘要	During their long evolutionary history, jellyfish have faced changes in multiple environmental factors, to which they may selectively fix adaptations, allowing some species to survive and inhabit diverse environments. Previous findings have confirmed the jellyfish's ability to synthesize large ATP amounts, mainly produced by mitochondria, in response to environmental challenges. This study characterized the respiratory chain from the mitochondria of the jellyfish Stomolophus sp2 (previously misidentified as Stomolophus meleagris). The in-gel activity from isolated jellyfish mitochondria confirmed that the mitochondrial respiratory chain contains the four canonical complexes I to IV and F0F1-ATP synthase. Specific additional activity bands, immunodetection, and mass spectrometry identification confirmed the occurrence of four alternative enzymes integrated into a branched mitochondrial respiratory chain of Stomolophus sp2: an alternative oxidase and three dehydrogenases (two NADH type II enzymes and a mitochondrial glycerol-3-phosphate dehydrogenase). The analysis of each transcript sequence, their phylogenetic relationships, and each protein's predicted models confirmed the mitochondrial alternative enzymes' identity and specific characteristics. Although no statistical differences were found among the mean values of transcript abundance of each enzyme in the transcriptomes of jellyfish exposed to three different temperatures, it was confirmed that each gene was expressed at all tested conditions. These first-time reported enzymes in cnidarians suggest the adaptative ability of jellyfish's mitochondria to display rapid metabolic responses, as previously described, to maintain energetic homeostasis and face temperature variations due to climate change.
英文关键词	Alternative enzymes; Medusae; Energetic metabolism; Mitochondria
语种	英语
WOS研究方向	Biophysics ; Cell Biology
WOS类目	Biophysics ; Cell Biology
WOS记录号	WOS:001143670300001
来源期刊	JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/298030
作者单位	CIAD - Centro de Investigacion en Alimentacion y Desarrollo; CIBNOR - Centro de Investigaciones Biologicas del Noroeste; CIBNOR - Centro de Investigaciones Biologicas del Noroeste
推荐引用方式 GB/T 7714	Nevarez-Lopez, C. A.,Muhlia-Almazan, A.,Gamero-Mora, E.,et al. The branched mitochondrial respiratory chain from the jellyfish Stomolophus sp2 as a probable adaptive response to environmental changes[J],2024,56(2).
APA	Nevarez-Lopez, C. A.,Muhlia-Almazan, A.,Gamero-Mora, E.,Sanchez-Paz, A.,Sastre-Velasquez, C. D.,&Lopez-Martinez, J..(2024).The branched mitochondrial respiratory chain from the jellyfish Stomolophus sp2 as a probable adaptive response to environmental changes.JOURNAL OF BIOENERGETICS AND BIOMEMBRANES,56(2).
MLA	Nevarez-Lopez, C. A.,et al."The branched mitochondrial respiratory chain from the jellyfish Stomolophus sp2 as a probable adaptive response to environmental changes".JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 56.2(2024).