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| DOI | 10.1002/aoc.7520 |
| Cerium-based metal-organic frameworks (MOFs) as a sustainable approach to mitigating environmental stress-induced intestinal ulcers in earthworms | |
| 发表日期 | 2024 |
| ISSN | 0268-2605 |
| EISSN | 1099-0739 |
| 英文摘要 | Exposure to environmental stresses such as heavy metal pollution, herbicides, and climate change may cause adverse effects on biological animals such as earthworms, leading to conditions including intestinal ulcers. This study outlines the potential of a cerium-based metal-organic framework (Ce-MOF) in healing alcohol-induced ulcers in earthworms. The Ce-MOF was synthesized via a solvothermal technique and analyzed using X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy. Ce-MOF exhibited a one-dimensional channel and demonstrated multi-enzyme-like activity. It was examined on earthworms suffering from ulcers caused by alcohol use. Examinations at a macroscopic level, histological analysis, and transmission electron microscopy images showed significant harm to the intestinal lining in ulcerated worms. The ulcer treatment with Ce-MOF substantially enhanced intestinal morphology, repaired the epithelial lining, and facilitated ulcer healing. Furthermore, Ce-MOF decreased the death rate and enhanced the weight of earthworms in comparison to untreated groups. This study emphasizes the potential of Ce-MOF as an innovative therapeutic agent for alcohol-induced ulcers, emphasizing its prospective uses in regenerative medicine and tissue regeneration. This research describes the design and investigation of a cerium-based metal-organic framework (Ce-MOF) for the treatment of alcohol-induced earthworm ulcers. Ce-MOF improved intestinal shape, epithelial lining, and ulcer healing. Ce-MOF reduced earthworm deaths and increased weight. Ce-MOF may be used in regenerative medicine and tissue regeneration to treat alcohol-induced ulcers. image |
| 英文关键词 | cerium-based MOF; earthworms; intestinal ulcers; metal-organic frameworks |
| 语种 | 英语 |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Applied ; Chemistry, Inorganic & Nuclear |
| WOS记录号 | WOS:001222708100001 |
| 来源期刊 | APPLIED ORGANOMETALLIC CHEMISTRY
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| 文献类型 | 期刊论文 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/297859 |
| 作者单位 | Egyptian Knowledge Bank (EKB); Assiut University; Egyptian Knowledge Bank (EKB); Assiut University; Egyptian Russian University; Egyptian Knowledge Bank (EKB); Assiut University |
| 推荐引用方式 GB/T 7714 | . Cerium-based metal-organic frameworks (MOFs) as a sustainable approach to mitigating environmental stress-induced intestinal ulcers in earthworms[J],2024. |
| APA | (2024).Cerium-based metal-organic frameworks (MOFs) as a sustainable approach to mitigating environmental stress-induced intestinal ulcers in earthworms.APPLIED ORGANOMETALLIC CHEMISTRY. |
| MLA | "Cerium-based metal-organic frameworks (MOFs) as a sustainable approach to mitigating environmental stress-induced intestinal ulcers in earthworms".APPLIED ORGANOMETALLIC CHEMISTRY (2024). |
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