CCPortal
DOI10.1136/bmjopen-2023-077129
Climate footprint of industry-sponsored clinical research: an analysis of a phase-1 randomised clinical study and discussion of opportunities to reduce its impact
Laroche, Jason Keith; Alvarenga, Rodrigo; Collins, Michael; Costelloe, Thomas; De Soete, Wouter; Faludi, Jeremy; Rens, Kristel
发表日期2024
ISSN2044-6055
起始页码14
结束页码1
卷号14期号:1
英文摘要Objective This study aims to calculate the global warming potential, in carbon dioxide (CO2) equivalent emissions, from all in-scope activities involved in a phase-1 clinical study.Design Retrospective analysis.Data source Internal data held by Janssen Pharmaceuticals.Studies included Janssen-sponsored TMC114FD1HTX1002 study conducted between 2019 and 2021.Main outcome Measure CO2 equivalents (CO2e) for in-scope clinical trial activities calculated according to intergovernmental panel on climate change 2021 impact assessment methodology.Results The CO2e emissions generated by the trial were 17.65 tonnes. This is equivalent to the emissions generated by driving an average petrol-fueled family car 71 004 km or roughly 1.8 times around the circumference of the Earth. Commuting to the clinical site by the study participants generated the most emissions (5419 kg, 31% of overall emissions), followed by trial site utilities (2725 kg, 16% of overall emissions) and site staff travel (2560 kg, 15% of overall emissions). In total, the movement of people (participant travel, site staff travel and trial site staff travel) accounted for 8914 kg or 51% of overall trial emissions.Conclusions Decentralised trial models which seek to bring clinical trial operations closer to the participant offer opportunities to reduce participant travel. The electrification of sponsor vehicle fleets and society's transition towards electric vehicles may result in further reductions.Trial registration number NCT04208061.
英文关键词Clinical Trial; Clinical trials; Health policy
语种英语
WOS研究方向General & Internal Medicine
WOS类目Medicine, General & Internal
WOS记录号WOS:001156806400007
来源期刊BMJ OPEN
文献类型期刊论文
条目标识符http://gcip.llas.ac.cn/handle/2XKMVOVA/296883
作者单位Johnson & Johnson; Johnson & Johnson USA; Janssen Biotech Inc; Delft University of Technology; Johnson & Johnson; Janssen Pharmaceuticals
推荐引用方式
GB/T 7714
Laroche, Jason Keith,Alvarenga, Rodrigo,Collins, Michael,et al. Climate footprint of industry-sponsored clinical research: an analysis of a phase-1 randomised clinical study and discussion of opportunities to reduce its impact[J],2024,14(1).
APA Laroche, Jason Keith.,Alvarenga, Rodrigo.,Collins, Michael.,Costelloe, Thomas.,De Soete, Wouter.,...&Rens, Kristel.(2024).Climate footprint of industry-sponsored clinical research: an analysis of a phase-1 randomised clinical study and discussion of opportunities to reduce its impact.BMJ OPEN,14(1).
MLA Laroche, Jason Keith,et al."Climate footprint of industry-sponsored clinical research: an analysis of a phase-1 randomised clinical study and discussion of opportunities to reduce its impact".BMJ OPEN 14.1(2024).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Laroche, Jason Keith]的文章
[Alvarenga, Rodrigo]的文章
[Collins, Michael]的文章
百度学术
百度学术中相似的文章
[Laroche, Jason Keith]的文章
[Alvarenga, Rodrigo]的文章
[Collins, Michael]的文章
必应学术
必应学术中相似的文章
[Laroche, Jason Keith]的文章
[Alvarenga, Rodrigo]的文章
[Collins, Michael]的文章
相关权益政策
暂无数据
收藏/分享

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。