气候变化领域集成服务门户(CCPortal): Chromosome-level genome assembly of Hippophae tibetana provides insights into high-altitude adaptation and flavonoid biosynthesis

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DOI	10.1186/s12915-024-01875-4
	Chromosome-level genome assembly of Hippophae tibetana provides insights into high-altitude adaptation and flavonoid biosynthesis
	Zhang, Guoyun; Song, Yating; Chen, Ning; Wei, Jihua; Zhang, Jianguo; He, Caiyun
发表日期	2024
EISSN	1741-7007
起始页码	22
结束页码	1
卷号	22 期号:1
英文摘要	Background As an endemic shrub of the Qinghai-Tibetan Plateau (QTP), the distribution of Hippophae tibetana Schlecht. ranges between 2800 and 5200 m above sea level. As the most basal branch of the Hippophae genus, H. tibetana has an extensive evolutionary history. The H. tibetana is a valuable tree for studying the ecological evolution of species under extreme conditions. Results Here, we generated a high-quality chromosome-level genome of H. tibetana. The total size of the assembly genome is 917 Mb. The phylogenomic analysis of 1064 single-copy genes showed a divergence between 3.4 and 12.8 Mya for H. tibetana. Multiple gene families associated with DNA repair and disease resistance were significantly expanded in H. tibetana. We also identified many genes related to DNA repair with signs of positive selection. These results showed expansion and positive selection likely play important roles in H. tibetana's adaptation to comprehensive extreme environments in the QTP. A comprehensive genomic and transcriptomic analysis identified 49 genes involved in the flavonoid biosynthesis pathway in H. tibetana. We generated transgenic sea buckthorn hairy root producing high levels of flavonoid. Conclusions Taken together, this H. tibetana high-quality genome provides insights into the plant adaptation mechanisms of plant under extreme environments and lay foundation for the functional genomic research and molecular breeding of H. tibetana.
英文关键词	Hippophae tibetana; Chromosome-level genome; Adaptation; Flavonoid biosynthesis
语种	英语
WOS研究方向	Life Sciences & Biomedicine - Other Topics
WOS类目	Biology
WOS记录号	WOS:001201816100005
来源期刊	BMC BIOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/296803
作者单位	Chinese Academy of Forestry; Research Institute of Forestry, CAF; State Key Laboratory of Tree Genetics & Breeding, CAF; Chinese Academy of Forestry; Research Institute of Forestry, CAF; Nanjing Forestry University
推荐引用方式 GB/T 7714	Zhang, Guoyun,Song, Yating,Chen, Ning,et al. Chromosome-level genome assembly of Hippophae tibetana provides insights into high-altitude adaptation and flavonoid biosynthesis[J],2024,22(1).
APA	Zhang, Guoyun,Song, Yating,Chen, Ning,Wei, Jihua,Zhang, Jianguo,&He, Caiyun.(2024).Chromosome-level genome assembly of Hippophae tibetana provides insights into high-altitude adaptation and flavonoid biosynthesis.BMC BIOLOGY,22(1).
MLA	Zhang, Guoyun,et al."Chromosome-level genome assembly of Hippophae tibetana provides insights into high-altitude adaptation and flavonoid biosynthesis".BMC BIOLOGY 22.1(2024).