气候变化领域集成服务门户(CCPortal): Dust particulate matter increases pulmonary embolism onset: A nationwide time-stratified case-crossover study in China

CCPortal

DOI	10.1016/j.envint.2024.108586
	Dust particulate matter increases pulmonary embolism onset: A nationwide time-stratified case-crossover study in China
	Zhang, Can; Zhao, Dan; Liu, Feng; Yang, Jing; Ban, Jie; Du, Peng; Lu, Kailai; Ma, Runmei; Liu, Yuanyuan; Sun, Qinghua; Chen, Siyu; Li, Tiantian
发表日期	2024
ISSN	0160-4120
EISSN	1873-6750
起始页码	39
卷号	39
英文摘要	Background: Particulate matter (PM) has been found to elevate the risk of pulmonary embolism (PE) onset. Among the contributors to PM, dust PM stands as the second natural source, and its emissions are escalating due to climate change. Despite this, information on the effect of dust PM on PE onset is scarce. Hence, this study aims to investigate the impacts of dust PM10, dust PM2.5-10, and dust PM2.5 on PE onset. Methods: A nationwide time-stratified case-crossover study was conducted between 2015 and 2020, using data from 18,616 PE onset cases across 1,921 hospitals in China. The analysis employed a conditional logistic regression model to quantify the associations between dust PM10, dust PM2.5-10, and dust PM2.5 and PE onset. Furthermore, the study explored the time-distributed lag pattern of the effect of dust PM on PE development. Stratified analyses were performed based on sex, age, region, and season. Results: Dust PM10, dust PM2.5-10, and dust PM2.5 exhibited significant health effects on PE onset, particularly concerning exposure on the same day. The peak estimates were observed at lag 01 day, with the odds ratio being 1.011 [95 % confidence interval (CI): 1.003, 1.019], 1.014 (95 % CI: 1.003, 1.026), and 1.039 (95 % CI: 1.011, 1.068), for a 10 mu g/m3 increase in the concentration of dust PM10, dust PM2.5-10, and dust PM2.5, respectively. In addition, the study identified a higher risk of PE onset associated with dust PM exposure during the warm season than that in cool season, particularly for dust PM2.5. Conclusions: The findings from this study suggest that short-term exposure to dust PM, particularly dust PM2.5, may trigger PE onset, posing a significant health threat. Implementing measures to mitigate dust PM emissions and protect patients with PE from dust PM exposure is imperative.
英文关键词	Pulmonary embolism; Dust; PM2.5; Morbidity; Climate change
语种	英语
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Environmental Sciences
WOS记录号	WOS:001215734300001
来源期刊	ENVIRONMENT INTERNATIONAL
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/291010
作者单位	Chinese Center for Disease Control & Prevention; National Institute of Environmental Health, Chinese Center for Disease Control & Prevention; Chinese Center for Disease Control & Prevention; National Institute of Environmental Health, Chinese Center for Disease Control & Prevention; Lanzhou University; Shanghai Jiao Tong University; Fudan University
推荐引用方式 GB/T 7714	Zhang, Can,Zhao, Dan,Liu, Feng,et al. Dust particulate matter increases pulmonary embolism onset: A nationwide time-stratified case-crossover study in China[J],2024,39.
APA	Zhang, Can.,Zhao, Dan.,Liu, Feng.,Yang, Jing.,Ban, Jie.,...&Li, Tiantian.(2024).Dust particulate matter increases pulmonary embolism onset: A nationwide time-stratified case-crossover study in China.ENVIRONMENT INTERNATIONAL,39.
MLA	Zhang, Can,et al."Dust particulate matter increases pulmonary embolism onset: A nationwide time-stratified case-crossover study in China".ENVIRONMENT INTERNATIONAL 39(2024).