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| DOI | 10.1016/j.heliyon.2024.e26765 |
| Effects of temperature anomaly on sperm quality: A multi-center study of 33,234 men | |
| Xiao, Lina; Wang, Qiling; Ni, Haobo; Xu, Ting; Cai, Xiaoyan; Dai, Tingting; Wang, Lingxi; Song, Chunying; Li, Yushan; Li, Fuping; Meng, Tianqing; Sheng, Huiqiang; Yu, Xiaolin; Zeng, Qinghui; Guo, Pi; Zhang, Xinzong | |
| 发表日期 | 2024 |
| EISSN | 2405-8440 |
| 起始页码 | 10 |
| 结束页码 | 5 |
| 卷号 | 10期号:5 |
| 英文摘要 | Backgrounds: Global fertility rates continue to decline and sperm quality is a prime factor affecting male fertility. Both extreme cold and heat have been demonstrated to be associated with decreased sperm quality, but no epidemiological studies have considered human adaptation to long-term temperature. Our aim was to conduct a multi-center retrospective cohort study to investigate exposure-response relationship between temperature anomaly (TA) that deviate from long-term climate patterns and sperm quality. Methods: A total of 78,952 semen samples measured in 33,234 donors from 6 provincial human sperm banks in China were collected. This study considered heat and cold acclimatization to prolonged exposure in humans and explored the exposure-response relationship between TAs and sperm quality parameters (sperm concentrations, sperm count, progressive motility, progressive sperm count, total motility and total motile sperm count) during the hot and cold seasons, respectively. Linear mixed models and generalized linear models were built separately for specific centers to pool in a meta-analysis to obtain the pooled effect of TA on sperm quality, considering repeated measurements data structure and spatial heterogeneity. Results: We identified an inverted U-shaped exposure-response relationship between TA and sperm quality during the hot season. Significant negative effect of anomalous cold on sperm quality during the hot season was found after additional adjustment for Body mass index, marital status and childbearing history. The heat-related TA in hot season was significantly negatively associated with sperm concentration, progressive sperm count and total motile sperm count (all P- values<0.05). After adjusting the relative humidity, the cold -related TA in cold season was negatively associated with the sperm total motility (P-values<0.05). Conclusions: Our results suggest both heat -related and cold -related TAs are associated with decreased sperm quality. The findings highlight the importance of reducing exposure to anomalous temperatures to protect male fertility. |
| 英文关键词 | Climate change; Exposure-response relationship; Human adaptation; Sperm quality; Temperature anomaly |
| 语种 | 英语 |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| WOS记录号 | WOS:001195703200001 |
| 来源期刊 | HELIYON
 |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://gcip.llas.ac.cn/handle/2XKMVOVA/290793 |
| 作者单位 | Shantou University; Zhengzhou University; Sichuan University; Huazhong University of Science & Technology; Huazhong University of Science & Technology |
| 推荐引用方式 GB/T 7714 | Xiao, Lina,Wang, Qiling,Ni, Haobo,et al. Effects of temperature anomaly on sperm quality: A multi-center study of 33,234 men[J],2024,10(5). |
| APA | Xiao, Lina.,Wang, Qiling.,Ni, Haobo.,Xu, Ting.,Cai, Xiaoyan.,...&Zhang, Xinzong.(2024).Effects of temperature anomaly on sperm quality: A multi-center study of 33,234 men.HELIYON,10(5). |
| MLA | Xiao, Lina,et al."Effects of temperature anomaly on sperm quality: A multi-center study of 33,234 men".HELIYON 10.5(2024). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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