气候变化领域集成服务门户(CCPortal): Assessment of Dynamic Cerebral Autoregulation During Long-Term Exposure to High Altitude in Normal Subjects by Ultrasonography

CCPortal

DOI	10.1002/jum.16467
	Assessment of Dynamic Cerebral Autoregulation During Long-Term Exposure to High Altitude in Normal Subjects by Ultrasonography
	Liang, Yuan; Gao, Zi Zhao; Chen, Hong Yu; Gao, Hong Kui; Qiang, Xiao Peng; Wang, Jia
发表日期	2024
ISSN	0278-4297
EISSN	1550-9613
英文摘要	Purpose-To evaluate changes in dynamic cerebral autoregulation (CA) during short-term and long-term exposure to high altitude with ultrasonography, and also study the sex differences in the response of CA to altitude. Methods-We assessed the differences in dynamic CA and measured with Doppler ultrasound of the bilateral internal carotid artery (ICA), vertebral artery (VA), and middle cerebral artery (MCA) and the values of basic information within 48 hours and at 2 years after arrival at Tibet in 65 healthy Han young Chinese volunteers, meanwhile, we compared the resistance index (RI) and pulsatility index (PI) of the right MCA at inhale oxygen 8 minutes when a newcomer with 2 years after arrival at Tibet. Results-With 2 years of altitude exposure, the SaO(2) of all subjects was above 90%, the mean PEF, DAP, and HR values decreased, HGB increased compared within 48 hours in same-gender groups. Comparisons of cerebral hemodynamics between before 2 years and after 2 years within male and female groups, the mean RI and PI values of bilateral MCA after 2 years were significantly higher than before 2 years, at the same time, the mean RI and PI values of bilateral ICA were significant differences (P < .05) between male groups, with regard to female groups, showed that the mean RI and PI values of bilateral VA were significant differences (P < .05). Comparisons of Right MCA hemodynamics between after oxygen uptake 8 minutes and 2 years, the mean RI and PI values were no significant difference within male and female groups (P > .05). Conclusions-Acute mountain sickness could result from an alteration of dynamic autoregulation of cerebral blood flow, but the impaired autoregulation may be corrected with the extension of time, furthermore, the response of CA to altitude in males and females are different.
英文关键词	acute mountain sickness; cerebral blood flow; dynamic cerebral autoregulation; high altitude; hypoxia; ultrasonography
语种	英语
WOS研究方向	Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:001217072400001
来源期刊	JOURNAL OF ULTRASOUND IN MEDICINE
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/289969
作者单位	Air Force Military Medical University; Air Force Military Medical University
推荐引用方式 GB/T 7714	Liang, Yuan,Gao, Zi Zhao,Chen, Hong Yu,et al. Assessment of Dynamic Cerebral Autoregulation During Long-Term Exposure to High Altitude in Normal Subjects by Ultrasonography[J],2024.
APA	Liang, Yuan,Gao, Zi Zhao,Chen, Hong Yu,Gao, Hong Kui,Qiang, Xiao Peng,&Wang, Jia.(2024).Assessment of Dynamic Cerebral Autoregulation During Long-Term Exposure to High Altitude in Normal Subjects by Ultrasonography.JOURNAL OF ULTRASOUND IN MEDICINE.
MLA	Liang, Yuan,et al."Assessment of Dynamic Cerebral Autoregulation During Long-Term Exposure to High Altitude in Normal Subjects by Ultrasonography".JOURNAL OF ULTRASOUND IN MEDICINE (2024).