气候变化领域集成服务门户(CCPortal): Integrated Omics Approach to Discover Differences in the Metabolism of a New Tibetan Desmodesmus sp. in Two Types of Sewage Treatments

CCPortal

DOI	10.3390/metabo13030388
	Integrated Omics Approach to Discover Differences in the Metabolism of a New Tibetan Desmodesmus sp. in Two Types of Sewage Treatments
	Wang, Jinhu; Chen, Junyu; Zhang, Dongdong; Cui, Xiaomei; Zhou, Jinna; Li, Jing; Wei, Yanli; Bu, Duo
发表日期	2023
EISSN	2218-1989
卷号	13 期号:3
英文摘要	Microalgae are now widely applied in municipal (YH_3) and industrial sewage (YH_4) treatments. Through integrated omics analysis, we studied the similarities and differences at the molecular level between the two different types of sewage treatment processes. The most significantly enriched gene ontology (GO) terms in both types of sewage treatments were the ribosome, photosynthesis, and proteasome pathways. The results show that the pathways of differentially expressed genes (DEGs) and differentially accumulated metabolites (DAMs) were enriched for photosynthesis, glyoxylate and dicarboxylate metabolism, and carbon fixation in photosynthetic organisms. Considering YH_3 vs. YH_4, the metabolism of citrate, sedoheptulose-7P, and succinate was significantly upregulated. In addition, the results showed that the pathways of DEGs and DAMs were enriched in terms of amino acid metabolism and carotenoid biosynthesis in YH_4 vs. YH_3. The metabolism of S-Adenosyl-L-homocysteine was significantly downregulated, 2-oxobutanoate was significantly upregulated and downregulated, and the metabolism of abscisic acid glucose ester (ABA-GE) was also significantly upregulated. Overall, the results of this paper will help to improve the basic knowledge of the molecular response of microalgae to sewage treatments, and help design a response strategy based on microalgae for complex, mixed sewage treatments.
关键词	Tibetan Desmodesmus sp municipal sewage treatment heavy metal sewage treatment transcriptomics metabolomics
英文关键词	GREEN MICROALGAE; METABOLOMICS; REMOVAL; ACID
WOS研究方向	Biochemistry & Molecular Biology
WOS记录号	WOS:000958248700001
来源期刊	METABOLITES
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283819
作者单位	Tibet University
推荐引用方式 GB/T 7714	Wang, Jinhu,Chen, Junyu,Zhang, Dongdong,et al. Integrated Omics Approach to Discover Differences in the Metabolism of a New Tibetan Desmodesmus sp. in Two Types of Sewage Treatments[J],2023,13(3).
APA	Wang, Jinhu.,Chen, Junyu.,Zhang, Dongdong.,Cui, Xiaomei.,Zhou, Jinna.,...&Bu, Duo.(2023).Integrated Omics Approach to Discover Differences in the Metabolism of a New Tibetan Desmodesmus sp. in Two Types of Sewage Treatments.METABOLITES,13(3).
MLA	Wang, Jinhu,et al."Integrated Omics Approach to Discover Differences in the Metabolism of a New Tibetan Desmodesmus sp. in Two Types of Sewage Treatments".METABOLITES 13.3(2023).