气候变化领域集成服务门户(CCPortal): Tibetan medicine Bang Jian: a comprehensive review on botanical characterization, traditional use, phytochemistry, and pharmacology

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DOI	10.3389/fphar.2023.1295789
	Tibetan medicine Bang Jian: a comprehensive review on botanical characterization, traditional use, phytochemistry, and pharmacology
	Li, Yuan; Zhang, Jie; Fan, Jin-ya; Zhong, Shi-hong; Gu, Rui
发表日期	2023
EISSN	1663-9812
卷号	14
英文摘要	Tibetan medicine Bang Jian refers to a range of botanical drugs within the Gentiana genus. It serves as a prominent traditional Tibetan botanical drug primarily found in the ethnic minority regions of the Qinghai-Tibet Plateau in China. Traditionally, the dried flowers of Bang Jian, known as Longdanhua have been employed in Tibetan medicine to address detoxification, pharyngeal relief, acute and chronic bronchitis, bronchiectasis, lung infections, pulmonary fibrosis, and throat disorders. Surprisingly, there has been no comprehensive review published to date on Tibetan medicine Bang Jian. This passage systematically presents and critically assesses recent advancements in botanical characterization, traditional applications, phytochemistry, pharmacology, and clinical uses of Bang Jian, aiming to provide a scientific foundation for its reasonable use and further exploration. To date, researchers have isolated and identified 92 structurally diverse compounds, with a predominant presence of iridoids, flavonoids, xanthones, and triterpenoids. The crude extracts and metabolites derived from Bang Jian have been found to exhibit a wide range of pharmacological effects, encompassing anti-inflammatory, anti-tumor, anti-bacterial, antiviral, antioxidant, hepatoprotective properties, and protect the respiratory system. Nevertheless, detailed data on the biological effects, metabolic activities, and mechanistic research concerning active monomer metabolites remain insufficient. Consequently, there is a pressing need for comprehensive and in-depth research to guide rational clinical drug usage and evaluate the medicinal attributes of Bang Jian.
关键词	Bang Jian botanical characterization traditional use phytochemistry pharmacological activities
英文关键词	GENTIANA-VEITCHIORUM HEMSL.; CHEMICAL-CONSTITUENTS; OXIDATIVE STRESS; FLAVONOIDS
WOS研究方向	Pharmacology & Pharmacy
WOS记录号	WOS:001131679300001
来源期刊	FRONTIERS IN PHARMACOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283694
作者单位	Chengdu University of Traditional Chinese Medicine; Southwest Minzu University; Chengdu University of Traditional Chinese Medicine; Chengdu University of Traditional Chinese Medicine
推荐引用方式 GB/T 7714	Li, Yuan,Zhang, Jie,Fan, Jin-ya,et al. Tibetan medicine Bang Jian: a comprehensive review on botanical characterization, traditional use, phytochemistry, and pharmacology[J],2023,14.
APA	Li, Yuan,Zhang, Jie,Fan, Jin-ya,Zhong, Shi-hong,&Gu, Rui.(2023).Tibetan medicine Bang Jian: a comprehensive review on botanical characterization, traditional use, phytochemistry, and pharmacology.FRONTIERS IN PHARMACOLOGY,14.
MLA	Li, Yuan,et al."Tibetan medicine Bang Jian: a comprehensive review on botanical characterization, traditional use, phytochemistry, and pharmacology".FRONTIERS IN PHARMACOLOGY 14(2023).