气候变化领域集成服务门户(CCPortal): Duodenal intestinal flora diversity of Tibetan pigs is lower than that of York pigs based on 16S rRNA analysis

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DOI	10.35495/ajab.2023.130
	Duodenal intestinal flora diversity of Tibetan pigs is lower than that of York pigs based on 16S rRNA analysis
	Sun, Wenli; Wang, Yu; Zhang, Jian; Yin, Yikai; Duan, Mengqi; Yangzom, Chamba; Shang, Peng
发表日期	2024
ISSN	2307-8553
卷号	2024 期号:1
英文摘要	Tibetan pigs exhibit remarkable characteristics, particularly their heightened tendency for fat deposition and increased resistance to diseases in comparison to Yorkshire pigs. Surprisingly, there has been a noticeable scarcity of research delving into the underlying mechanisms responsible for these advantageous traits, especially from the perspective of intestinal microorganisms, particularly those inhabiting the duodenum. To bridge this research gap, the study harnessed 16S rRNA sequencing to conduct a comprehensive examination of the duodenal microbiota in Tibetan and Yorkshire pigs. The results stemming from amplicon sequencing of duodenal contents unveiled that at the phylum level, Firmicutes dominated the duodenal microbiota in both Tibetan and Yorkshire pigs. Intriguingly, Tibetan pigs showcased a significantly reduced proportion of Bacteroidetes in comparison to Yorkshire pigs (P < 0.05), leading to a substantially higher Firmicutes to Bacteroidetes ratio in Tibetan pigs (55.95) as opposed to Yorkshire pigs (3.86) (P < 0.05). Of remarkable note, at the genus level, Tibetan pigs displayed a significantly elevated relative abundance of Lactobacillus spp. when compared to Yorkshire pigs (P < 0.01). Functional predictions pertaining to the duodenal microbiota in both pig breeds primarily revolved around amino acid metabolism, cofactor and vitamin metabolism, terpene and polyketide metabolism, amino acid derivative metabolism, and lipid metabolism. This study underscores the intricate and interdependent relationship between the composition and abundance of the duodenal microbiota and the unique characteristics of fat deposition and disease resistance in Tibetan pigs. It suggests Lactobacillus spp. as significant contributors to fat deposition, the development of the duodenal intestinal barrier, and immune function. Additionally, the Firmicutes-to-Bacteroidetes ratio appears to be associated with fat deposition. These findings provide valuable insights that can serve as a valuable reference for future endeavors related to the development and utilization of Tibetan pigs.
关键词	Tibetan pigs Duodenum Intestinal microorganisms Fat deposition Disease resistance
英文关键词	SEQUENCES; COMMUNITY; PROFILES
WOS研究方向	Agriculture, Multidisciplinary
WOS记录号	WOS:001159714200010
来源期刊	ASIAN JOURNAL OF AGRICULTURE AND BIOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283556
作者单位	Tibet Agriculture & Animal Husbandry University
推荐引用方式 GB/T 7714	Sun, Wenli,Wang, Yu,Zhang, Jian,et al. Duodenal intestinal flora diversity of Tibetan pigs is lower than that of York pigs based on 16S rRNA analysis[J],2024,2024(1).
APA	Sun, Wenli.,Wang, Yu.,Zhang, Jian.,Yin, Yikai.,Duan, Mengqi.,...&Shang, Peng.(2024).Duodenal intestinal flora diversity of Tibetan pigs is lower than that of York pigs based on 16S rRNA analysis.ASIAN JOURNAL OF AGRICULTURE AND BIOLOGY,2024(1).
MLA	Sun, Wenli,et al."Duodenal intestinal flora diversity of Tibetan pigs is lower than that of York pigs based on 16S rRNA analysis".ASIAN JOURNAL OF AGRICULTURE AND BIOLOGY 2024.1(2024).