气候变化领域集成服务门户(CCPortal): Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet

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DOI	10.4103/IJO.IJO_1546_23
	Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet
	Cai, Chunyang; Ma, Yingyan; He, Shuai; Meng, Chunren; Gu, Chufeng; He, Jiangnan; Lhamo, Thashi; Draga, Deji; Zhou, Chuandi; Qiu, Qinghua
发表日期	2024
ISSN	0301-4738
EISSN	1998-3689
起始页码	S240
结束页码	S247
卷号	72 期号:SUPPL 2
英文摘要	Purpose: This study aimed to explore the influence of high altitude on myopia, macular choroidal thickness (mCT), and macular retinal thickness (mRT) in adolescents. Methods: Two schools, one in Shanghai (at sea level) and one in Shigatse, Tibet (more than 4000 m above sea level), were selected. Refractive error was measured by an autorefractor instrument and subjective refraction, and mCT and mRT were measured at three concentric circles by optical coherence tomography. Student's t-test, Chi-square test, and multiple linear regression analyses were used to analyze the data. Results: A total of 1114 participants (657 and 457 in Shanghai and Tibet, respectively) were enrolled in this cross-sectional study. The average age of the participants was 18.81 +/- 1.10 years, and 44.34% were males. The spherical equivalent (SE) of adolescents in Shanghai was significantly lower than that of adolescents in Tibet (-4.14 +/- 2.37 D and-2.12 +/- 1.87 D, P < 0.01). The prevalence of myopia and high myopia among adolescents in Shanghai (94.52%, 19.48%) was significantly higher than those among adolescents in Tibet (44.74%, 2.41%) (P < 0.01). The mCT of Tibetan adolescents was significantly thicker than that of Shanghai adolescents (295.80 +/- 62.46 mu m and 218.71 +/- 61.42 mu m, P < 0.01), especially the central mCT. The mRT of Tibetan adolescents was also thicker than that of Shanghai adolescents (301.42 +/- 23.26 mu m and 281.04 +/- 12.24 mu m, P < 0.01). Conclusions: Compared with Shanghai adolescents, the choroid of Tibet adolescents is thicker, and the myopia prevalence is lower. It is speculated that increased altitude is associated with the thickening of mCT and a low myopia prevalence.
关键词	Adolescents choroidal thickness high altitude myopia retinal thickness
英文关键词	PREVALENCE; CHILDREN; LIGHT
WOS研究方向	Ophthalmology
WOS记录号	WOS:001150939400017
来源期刊	INDIAN JOURNAL OF OPHTHALMOLOGY
文献类型	期刊论文
条目标识符	http://gcip.llas.ac.cn/handle/2XKMVOVA/283020
作者单位	Shanghai Jiao Tong University; Shanghai Jiao Tong University
推荐引用方式 GB/T 7714	Cai, Chunyang,Ma, Yingyan,He, Shuai,et al. Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet[J],2024,72(SUPPL 2).
APA	Cai, Chunyang.,Ma, Yingyan.,He, Shuai.,Meng, Chunren.,Gu, Chufeng.,...&Qiu, Qinghua.(2024).Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet.INDIAN JOURNAL OF OPHTHALMOLOGY,72(SUPPL 2).
MLA	Cai, Chunyang,et al."Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet".INDIAN JOURNAL OF OPHTHALMOLOGY 72.SUPPL 2(2024).